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Information
| Code | BL489 |
| Name | Organel Genetics |
| Term | 2024-2025 Academic Year |
| Semester | 7. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. HASAN BASRİ İLA |
| Course Instructor |
1 2 |
Course Goal / Objective
The aim of this course is to teach the basic information about mitochondria structure, genome and causes of damage in this genome.
Course Content
This course includes mitochondrial structure and especially mitochondrial genetics.
Course Precondition
None
Resources
Clinical Mitochondrial Medicine. Author: Michael J. Keogh, Patrik F. Chinnery. Publisher: Celsus Bookstore. Dough Type: Coated. Number of Pages: 432. Size: 16 x 24. First Printing Year: 2021. Number of Printings: 1st Edition. Language Turkish.
Notes
Praise for Mitochondria and the Future of Medicine Author: Lee Know Publisher: Academician Bookstore
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | The student classifies the structure of mitochondria, their number and function in the cell in detail. |
| LO02 | Comprehend the information about mitochondrial genome and explain its interaction with nuclear genome |
| LO03 | Sorts free radicals of mitochondrial origin |
| LO04 | Discuss the causes and consequences of mitochondrial diseases. |
| LO05 | Define the role of mitochondria in energy production and explain the ATP synthesis mechanism. |
| LO06 | Explain the process of mitochondrial biogenesis and the regulation of related genes. |
| LO07 | Evaluate the role of mitochondria in apoptosis and cellular aging. |
| LO08 | Analyze the effects of mitochondria on cellular metabolism. |
| LO09 | Explain mitochondrial transport systems and the functions of proteins involved in these processes. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explain the basic concepts and principles in biology | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | The knowledge gained in the field of biology combine with information from other sciences. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Identifies problems in the field of biology and apply methods for their solution | 3 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Describes the method of producing scientific knowledge in the field of biology | |
| PLO05 | Bilgi - Kuramsal, Olgusal | They will receive information on the biology area, in order to classify it uses and purposes. | 2 |
| PLO06 | Bilgi - Kuramsal, Olgusal | They use advanced theoretical and practical knowledge that obtain in biology field. | 2 |
| PLO07 | Bilgi - Kuramsal, Olgusal | They are Field-related issues can inform the relevant persons and institutions, They share ideas and problems relating to suggestions as the written, oral and Visual to expert or transfer to non-experts. | |
| PLO08 | Bilgi - Kuramsal, Olgusal | They can take responsibility as individuals and team members to solve unpredictable problems encountered in applications related to the field. | 3 |
| PLO09 | Bilgi - Kuramsal, Olgusal | they can take an active role as a member of the execution team the planning of projects related to the field. | 3 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | They know that life-long learning process and act accordingly. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They will increase the knowledge and experience outside major issues with specific elective courses in different fields of biology. | 2 |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They speak English enough to communicate with colleagues to understand the basic concepts of biology. | |
| PLO13 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They both with colleagues, as well as areas with non-person establishes ethical uses of information and communication technology. In addition to professional development, in line with the interests and abilities of scientific, social, constantly improves itself by identifying learning needs in cultural and artistic fields. | |
| PLO14 | Yetkinlikler - Öğrenme Yetkinliği | They assesses developments in biology versatile using scientific methods and techniques | 3 |
| PLO15 | Yetkinlikler - Öğrenme Yetkinliği | They know the importance of personal development and enforces the need. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Ultrastructure of mitochondria | Scanning and reading different sources | Öğretim Yöntemleri: Soru-Cevap |
| 2 | Number and tasks of the mitochondria in the cell | Scanning and reading different sources | Öğretim Yöntemleri: Tartışma |
| 3 | Mitochondrial DNA and genes on it | Scanning and reading different sources | Öğretim Yöntemleri: Anlatım |
| 4 | Protein synthesis and molecular traffic in mitochondria | Scanning and reading different sources | Öğretim Yöntemleri: Gösteri |
| 5 | Electron transfer in oxygen respiration and ATP synthesis | Scanning and reading different sources | Öğretim Yöntemleri: Benzetim |
| 6 | Formation of free radicals from mitochondria | Scanning and reading different sources | Öğretim Yöntemleri: Beyin Fırtınası |
| 7 | Free radical types | Scanning and reading different sources | Öğretim Yöntemleri: Gösterip Yaptırma |
| 8 | Mid-Term Exam | An overview | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | DNA and other molecular damages caused by free radicals | Scanning and reading different sources | Öğretim Yöntemleri: Beyin Fırtınası |
| 10 | High mutation frequency of mitochondrial DNA and its causes | Scanning and reading different sources | Öğretim Yöntemleri: Soru-Cevap |
| 11 | Human diseases causing by damaging mitochondria | Scanning and reading different sources | Öğretim Yöntemleri: Problem Çözme |
| 12 | Human diseases caused by damaged mitochondria | Scanning and reading different sources | Öğretim Yöntemleri: Tartışma |
| 13 | Mitochondrial origin of Parkinson's and Alzheimer's disease | Scanning and reading different sources | Öğretim Yöntemleri: Soru-Cevap |
| 14 | Migration of mitochondrial DNA and its relationship with cancer | Scanning and reading different sources | Öğretim Yöntemleri: Örnek Olay |
| 15 | Reporting of detected mitochondrial DNA mutations. | Scanning and reading different sources | Öğretim Yöntemleri: Grup Çalışması |
| 16 | Term Exams | An overview | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | An overview | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 24 | 24 |
| Total Workload (Hour) | 88 | ||
| Total Workload / 25 (h) | 3,52 | ||
| ECTS | 4 ECTS | ||