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Information
| Code | TL122 |
| Name | Basic Biochemistry |
| Term | 2024-2025 Academic Year |
| Semester | 2. Semester |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Ön Lisans Dersi |
| Type | Normal |
| Label | VK Vocational Knowledge Courses C Compulsory |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. ŞULE SULTAN MENZİLETOĞLU YILDIZ |
| Course Instructor |
Doç. Dr. SEDEFGÜL YÜZBAŞIOĞLU ARIYÜREK
(A Group)
(Ins. in Charge)
Prof. Dr. ŞULE SULTAN MENZİLETOĞLU YILDIZ (A Group) (Asst. Ins.) |
Course Goal / Objective
Making biochemical analysis and testing to gain competency.
Course Content
Introduction to Biochemistry, Elemental composition of the human body; Biochemical significance of cells and cellular organelles; Water and electrolytes, carbohydrates, lipids, amino acids, proteins, enzymes, vitamins, nucleic acid structures, properties, and biological functions. Carbohydrates; lipids, amino acids, metabolism of nucleic acids and proteins.
Course Precondition
None
Resources
Lesson Notes
Notes
Wictor W. Rodwell, David A. Bender, Kathleen M. Botham, Peter J. Kennelly, P. Anthony Weil. Harper'ın Resimli Biyokimyası, ISBN: 9789752777767, 804 sayfa, 2019 Lipincot's Biyokimya D. L., Nelson and M. M., Cox. Lehninger Biyokimyanın İlkeleri. Çeviri editörü Prof. Dr. Nedret KILIÇ, 2005, Palme Yayıncılık R, Harvey and P.C. Champe. Lippincott Biyokimya. Çevirmen: Doç.Dr. Engin Ulukaya, 2007, Nobel Tıp Kitabevi.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explains basic information about the structures, functions and metabolisms of biomolecules that form the basic structure of the human body. |
| LO02 | Applying theoretical knowledge in laboratory analyses. |
| LO03 | Define the tools and equipments used in biochemistry laboratories. |
| LO04 | Lists basic information regarding the preparation and properties of biochemical solutions. |
| LO05 | Explains the measurement methods. |
| LO06 | Explain the structure and function of the building blocks forming the living organism. |
| LO07 | It expresses the conformational structures of carbohydrates, lipids, amino acids, peptides and proteins. |
| LO08 | Illustrate the functions of biomolecules in living things. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explains the basis of human normal structure and function | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Defines disinfection, sterilization and hygiene. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Recognizes laboratory tools and materials, lists measurement methods. | 2 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Explains the procedures to be performed in these phases using detailed information on the preanalytical, analytical and postanalytical phases of measurements. | 3 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Receives and accepts biological materials taken from the patient, prepares them for analysis and ensures that they are preserved under appropriate conditions if necessary. | |
| PLO06 | Bilgi - Kuramsal, Olgusal | Performs internal and external quality control studies of the analyzes, analyzes patient samples after applying daily control procedures, checks the results and reports to the laboratory specialist. | 4 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Performs the calibration and maintenance of laboratory equipments, have them to be calibrated and maintained and monitored by authorized persons as needed, so that they work most efficiently | |
| PLO08 | Bilgi - Kuramsal, Olgusal | Determines inaduquaciesis in the laboratory | 3 |
| PLO09 | Bilgi - Kuramsal, Olgusal | Knows the critical values and provides coordination by reporting the results to the clinician in the most appropriate and fast manner. | 2 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | After graduation, he/she develops himself/herself and his/her career by following technological developments and critically evaluating the information he/she has learned with his/her own knowledge. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Having professional and ethical responsibility, they communicate well with colleagues, patients and physicians. | |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Uses at least one foreign language to follow developments in his field and to communicate with colleagues adequately. | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Takes measures regarding health, biosafety and occupational safety in the work environment. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to Biochemistry; Structuring studies in biological systems; Elemental composition of the human body; Biochemical significance of cells and organelles. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım |
| 2 | The structure of carbohydrates, classification, functions. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 3 | Carbohydrate metabolism disorders. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Soru-Cevap, Deney / Laboratuvar |
| 4 | The structure of the enzyme, properties and classification; Factors affecting enzyme activity; The regulation of enzyme activity; The importance of enzymes in the diagnosis of disease. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösterip Yaptırma |
| 5 | The structure of the lipids, properties and classification; Factors affecting enzyme activity; The regulation of enzyme activity; The importance of enzymes in the diagnosis of disease. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Tartışma |
| 6 | Lipid metabolism; Cholesterol metabolism; Lipid metabolism disorders. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 7 | Structure of proteins, classification and functions; Protein metabolism | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 8 | Mid-Term Exam | Exam preparation | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Protein metabolism II; Urea cycle; Protein metabolism. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 10 | Hemoglobin and myoglobin structure, function; Both synthesis and degradation; Jaundice. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Tartışma, Gösteri |
| 11 | The structure and metabolism of nucleotides. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | DNA structure, properties, function replication. RNA structure, properties, protein synthesis. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Soru-Cevap, Deney / Laboratuvar |
| 13 | Classification of vitamins, biological significance and function. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | Minerals and water features, functions and metabolism. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | The structure of hormones, classification | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar, Tartışma |
| 16 | Term Exams | Exam preparation | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Exam preparation | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 5 | 5 |
| Final Exam | 1 | 5 | 5 |
| Total Workload (Hour) | 80 | ||
| Total Workload / 25 (h) | 3,20 | ||
| ECTS | 3 ECTS | ||