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Information
| Code | MED100 |
| Name | Phase I- Normal Structure and Function/ Cell-Tissue, Human Sciences |
| Term | 2024-2025 Academic Year |
| Term | 1. Term |
| Duration (Week) | 36 Week |
| ECTS | 40 ECTS |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Tıp - Kurul |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Öğr. Gör. Aslı BOZ |
Course Goal / Objective
Understanding normal development, structure and function of human body and intellect in accordance to all phases of life-time, having information about the interaction between body and intellect, using health concepts in proper ways and knowing how to use these information, learning basic approaches about person-to-person communication and attainment of this ability, appreciating the relation between medical sciences and culture, art and social sciences are all main themes of this course.
Course Content
This course continues 36 weeks and includes understanding of normal structures of human body and their functions at the levels of conceptions such as molecules, cells and tissues. Additionally, this course contains protection of health and ethical notion issues. Also, it contains first steps about attainment education on models. Orientation week, first step communication module, emergency health course and health institutions visits, all are the essential parts of this course.
Course Precondition
Succeeding in the Course Board
Resources
Albert B, Johnson A, Lewis J, Raff M, Robert K and Walter P. Moleculer Biology of the Cell, Fourth Edition, Garland Science, Newyork (2002), Anatomi Arıncı Kaplan, Elhan Alaittin, 1-2 cilt Güneş Kitabevi, 3. baskı Ankara, Biyokimya laboratuvar Uygulamaları, (H.Aydın, F.Girgin), EÜTF, 1998, Biyofizik laboratuvar Kılavuzları, Fizyoloji Laboratuvar Kılavuzları
Notes
Lecture Notes, Presentations, Textbooks, Experiments, Homeworks, Laboratory Practices
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explains the structure and functions of the cell, their physiological mechanisms and bioelectrical events. |
| LO02 | Explains the structure and functions of biochemical molecules involved in metabolism. |
| LO03 | Knows the structure and function of genetic material (DNA and RNA), gene expression, genome structure, nucleic acid metabolism and the use of DNA in medicine, the basic principles of heredity. |
| LO04 | Recognizes different cell types and normal structures of basic tissues at microscopic level. |
| LO05 | Explain the structure and function of the basic tissues of the body. |
| LO06 | Applies experiments related to basic biochemical and bioelectrical events in our body in laboratory environment. |
| LO07 | Defines the features of the anatomical formations of the movement system and the head-neck region, their structure and function relations, and Shows them on the model. |
| LO08 | Explains the structural and functional properties of the structures that make up the hemopoietic and immune systems, tells the basic principles of immunity and the basic immunological features of host-microorganism relations. |
| LO09 | Defines the determinants of health and contemporary health care approach. |
| LO10 | Defines the social medicine approach and the structures in the field of health. |
| LO11 | Defines the basics of behavioral sciences and psychological concepts. |
| LO12 | Learns and Applies basic professional skills on model. |
| LO13 | Defines basic approaches in human-to-human communication and gains effective communication and listening skills. |
| LO14 | Does group work on health-related social issues to improve research, communication and presentation skills. |
| LO15 | Integrates normal structure-function information from different disciplines/systems with abnormal structure-function information on a case-by-case basis |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To explain the normal structure, function, development and interaction of the human body and mind at all stages of life. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Common physical and mental disorders-diseases; can list and explain its epidemiology, pathology, symptoms, signs, prognosis and treatment. | 2 |
| PLO03 | Bilgi - Kuramsal, Olgusal | She/He has knowledge of preventive medicine methods and ethical principles in the creation of healthy living conditions and the prevention of diseases. | 5 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Should be able to identify current, reliable diagnostic methods and appropriate pharmacological, physical, nutritional and psychosocial treatment methods in diseases that are common in our country. | 4 |
| PLO05 | Bilgi - Kuramsal, Olgusal | She/he comprehends, analyzes and evaluates the health and disease components, process and outcome, uses evidence-based medicine methods in updating information and in patient treatment, adopts the principle of making decisions in line with ethical principles by evaluating the patient's preference, own experience and the most valid evidence. | 1 |
| PLO06 | Bilgi - Kuramsal, Olgusal | She/he takes an accurate, comprehensive and problem-oriented anamnesis, can approach the individual systematically by physical examination and mental evaluation, and decides by respecting the patient's privacy, secrets, honor, beliefs, cultural differences, and sexual preference. | 1 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Provides first aid and basic life support and plans the next process in cases where there may be significant loss of function and organ, requiring urgent intervention. | |
| PLO08 | Bilgi - Kuramsal, Olgusal | Makes differential diagnosis with a holistic approach to the patient, has knowledge, skills and competence in rational diagnosis and treatment planning, managing the patient and the disease, takes responsibility individually and as a team member in unexpected situations, monitors and owns the patient. | 1 |
| PLO09 | Bilgi - Kuramsal, Olgusal | Provides health education for the individual, family and society, carries out studies related to the field individually or as a team member, provides consultancy, supervision, expertise and leadership. | 2 |
| PLO10 | Bilgi - Kuramsal, Olgusal | Within the framework of the project it will carry out, it plans and manages the development and training of its employees, monitors and evaluates the process, and collaborates with other disciplines. | 1 |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Has the ability to communicate interculturally, can communicate effectively with patients, colleagues and other segments of the society, supports her/his thoughts and solution proposals with quantitative and qualitative data, and conveys them verbally and in writing, using Turkish correctly. | 3 |
| PLO12 | Beceriler - Bilişsel, Uygulamalı | Develops positive attitudes and behaviors towards lifelong learning, adopts the universal conditions required by the medical profession. | 1 |
| PLO13 | Beceriler - Bilişsel, Uygulamalı | Philosophy of science has the knowledge of the limits, accuracy, validity and reliability of information, knows the ways to reach the information and evaluates the information using critical thinking skills, determines the learning needs and resources related to medicine, and directs the learning by using the resources effectively. | 3 |
| PLO14 | Beceriler - Bilişsel, Uygulamalı | In addition to her professional development, she constantly improves herself/himself in cultural, artistic and social fields, and takes part in social responsibility projects with other professional groups. | 3 |
| PLO15 | Beceriler - Bilişsel, Uygulamalı | Can use medical information and communication technologies along with computer software at the level required by the field. | 2 |
| PLO16 | Yetkinlikler - Öğrenme Yetkinliği | Understands the social environment and behavioral relationship and interaction of health, comprehends its social and behavioral aspects and socioeconomic effects, monitors and evaluates health-related events and developments on the agenda of the society and the world. | |
| PLO17 | Yetkinlikler - Öğrenme Yetkinliği | She/he keeps accurate and reliable records, collects data, analyzes and interprets epidemic, clinical and laboratory data, and acts in accordance with ethical principles in sharing the results. | 5 |
| PLO18 | Yetkinlikler - Öğrenme Yetkinliği | She/he is sensitive to her/his own mental and physical health, employee health, environment and occupational safety, individual and public health, takes responsibility, develops a professional attitude and becomes a role model for the society with its behaviors. | 2 |
| PLO19 | Yetkinlikler - Öğrenme Yetkinliği | Knows the basic health legislation, acts in accordance with the laws, regulations and ethical rules regarding their rights and responsibilities as an individual. | 1 |
| PLO20 | Yetkinlikler - Öğrenme Yetkinliği | She/he uses her/his professional autonomy, has sufficient experience to perform clinical practices at national standards and perform preventive medicine services. He can follow a foreign language at least European Language Portfolio B1 information and communicate with his colleagues. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | The opening, The First Step Course and The introduction of departments. | The student researches and reads the relevant sections before the lesson. | Öğretim Yöntemleri: Anlatım, Grup Çalışması |
| 2 | Scientific method and biological concepts, The origin and evolution living things, Introduction to Biochemistry, Atomic structure and biochemical bonds, The chemical structure of organic compounds, The basic concepts of public health, Social medicine and history, Preventive medicine, Primary care physician practices, Measurement sensible digits and the SI system, Scaling and function relationship of magnitude, First aid course, Hand washing and gloving skills. | The student researches and reads the relevant sections before the lesson. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 3 | Biological concepts, The origin and evolution living things, Introduction to Biochemistry, Atomic structure and biochemical bonds, The chemical structure of organic compounds, The basic concepts of public health, Social medicine and history, Preventive medicine, Primary care physician practices, Measurement sensible digits and the SI system, Scaling and function relationship of magnitude, First aid course, Hand washing and gloving skills. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 4 | The objective of a being a physician and a social physician, bimolecular and biochemical methods, the main structure amino acid and proteins, The place of human in ecosystem, The ecologic pyramids and bioenergy, Interaction of human and ecosystem, The modern health concepts, the ability to hand washing and gloves wearing, Biogenesis, The bacteria cells, the fungus cells and fungus, the titration laboratory. | Preparatory work for the course | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Beyin Fırtınası |
| 5 | Cellular macromolecules and fluids, cell theory, cell membranes, organelles, cell skeleton, basic structure of carbohydrates, basic structure of lipids and nucleic acids, the ability of hand washing and wearing gloves, first aid course. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 6 | Diffusion through cell membrane, Basic structure of lipids, integrative approach, diffusion, osmosis, plasmolysis, deplasmolysis, photosynthesis and cellular respiration experiment in plant cells, carbohydrates recognition reactions. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Grup Çalışması, Beyin Fırtınası, Deney / Laboratuvar |
| 7 | Vitamins and coenzymes, enzymes, endocytosis, excosystosis, specialization to the cell surface, Cell connections, cell conduction of impulses, catabolism, cell respiration, Energy, Power and metabolic rate, the ability to hand washing and wearing gloves. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Beyin Fırtınası |
| 8 | Enzyme kinetics, energy metabolism, oxidation and reduction reactions in biological systems, anabolism, photosynthesis, chemosynthesis, family health relationship. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Alıştırma ve Uygulama, Beyin Fırtınası, Deney / Laboratuvar |
| 9 | I. Term Written Examination Committee | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav |
| 10 | Definition of Histology and Cytology, tissue preparation and analysis methods, electron microscopy, mechanical properties of biological solids, accidents and airbags, general analysis of metabolism, control of cell cycle, mitosis and meiosis, division of labor between organelles, the ability to taking blood and serum transfuse. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Beyin Fırtınası, Deney / Laboratuvar |
| 11 | Nutrition, trace elements, biological membranes and transport systems, digestion and absorption of carbohydrates, the body composition and body fluids, the laws of diffusion, osmotic transitions, carrier proteins, facilitated diffusion, active transport, homeostatic mechanisms, intercellular communication, Ballistocardiography, Sexual, asexual reproduction, gametogenesis and fertilization, the ability to taking blood and serum transfuse, Laboratory demonstration of proteins, visit the Institution application. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Beyin Fırtınası, Deney / Laboratuvar |
| 12 | Glycolysis and control of glycolysis, gluconeogenesis, pentose phosphate pathway, reproductive systems of human male and female, growth and development, Fluids and blood pressure, cells and cellular components, Cell nucleus and cell division, receptors, second messengers and signal transduction, the ability of taking blood and serum transfuse, Laboratory demonstration of Mitosis and enzymes. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 13 | Synthesis of fatty acids, prostaglandins, triglyceride and phospholipid metabolism, structure and biosynthesis of cholesterol, Genetic code and transcription, translation and protein synthesis, mutagens and mutations, the heat transfer mechanisms in body and temperature control, the ability to taking blood and serum transfuse, examination of testis and ovarium, sperm and ovum cells, determination of blood glucose. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 14 | Metabolism of cholesterol and bile acids, lipoprotein metabolism, digestion and absorption of proteins, amino acid metabolism and urea synthesis. DNA repair mechanisms, control of gene expression in prokaryotes and eukaryotes, DNA cloning, DNA library and DNA analysis methods, DNA isolation from tumor and normal tissue, DNA electrophoresis, cholesterol testing, blood sampling and the ability to perform serum transfusion. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 15 | Metabolism of cholesterol and bile acids, lipoprotein amino acid conversion to specific products, integration of metabolism, gene therapy and biotechnology, DNA sequence and genome structure, laboratory work for determination of urea. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 16 | Introduction to microbiology, bacterial genetics, transformation, transduction, conjugation, plasmids, purine-pyrimidine metabolism, the relationship between medicine and history, ability to perform injection. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 17 | II. Term Written Examination Committee | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav |
| 18 | Introduction to microbiology, bacterial genetics, transformation, transduction, conjugation, plasmids, purine-pyrimidine metabolism, the relationship between medicine and history, the ability to apply the injection. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 19 | Mendelian inheritance, single gene-related inheritance, Interaction between genes, structure of bacterial cell wall, Production of microorganisms, Introduction of behavioral sciences, definitions and concepts, an overview of the evolution of medicine, origin of medicine and antecedent medical applications, organization of DNA and RNA, determination of blood group, barr body and examination of polytene chromosomes, ability to perform injection. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 20 | DNA metabolism, Multiple allelism and blood groups, Multifactorial inheritance, pleiotropi, mitochondrial inheritance, penetrance, sex-dependent inheritance, linkage of gene analysis, behavior and genetics, neurobiological basis of behavior, Evolution of Western medicine, sterilization, disinfection, ability to perform injection, frog and rat dissection. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 21 | Genome analysis and gene mapping, investigation methods for genetic factors, DNA packaging and chromosome, genetics and metabolism of bacteria, structure of viruses and general characteristics, the proliferation of viruses and methods of diagnosis, biopsychosocial approach, adaptation and stress, psychodynamic basics of behavior: the defense mechanisms I, from Renaissance to XIX. Century and the present day medicine, The currents outside to Western medicine, ability to perform injection. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 22 | Protein synthesis and postsynthesis regulations, nucleic acids use in medicine, Cancer Biochemistry, Xenobiotics, viral interference and interferon, psychodynamic basics of behavior: Defense Mechanisms II, Personality Development, Headlines of Medical history, characteristics and mutations of chromosomes, chromosome obtaining methods, Autosomal disorders , ability to perform injection. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 23 | Gender disorders, chromosome separation, genetics of complex diseases, the genetic basis of antibody diversity, monoclonal antibodies and hybridomas, the genetic basis of differences in TCR, General parasitology, medically important protozoa, helminths and arthropods, examination of human chromosomes, karyotype and pedigree analysis, practical in vitro replication studies, ability to perform injection. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 24 | The genetic basis of the immune response, introduction to anatomy and anatomical terms, general information about the bones and joints, Introduction to Biophysics: system concept and bioenergetics, material transport and resting potential of the cell membrane, wound care skills. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 25 | III. Term Written Examination Committee | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav |
| 26 | Material transport in the cell membrane and resting potential, Subthreshold events and action potential , functional structure of the nerve cells, general information about muscles and blood vessels, innervations of the organs and formations, Shoulder bones: Bone and joints, Epithelial tissue: Protection and glandular epithelium, connective tissue and biochemistry of collagen, Wound care skills. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 27 | The muscles affecting shoulder joint, axillary and breast, biochemistry of muscles, histology of supportive tissue, connective and fatty tissue, ion balance and the resting membrane potential, Histology laboratory: Epithelial tissue, Anatomy Laboratory: Shoulder bones, the muscles affecting shoulder joint, wound care skills | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 28 | Subthreshold events and action potential, Ion channels and HH channel model, histology of supportive tissue, connective and fatty tissue, bones of the forearm and art. Cubiti, muscles of the arm, wrist bones and joints, Functional anatomy of hand, upper extremity nerves and lesions, local potentials, action, Anatomy Laboratory: axillary and breast, arm zone, the bones of the forearm, and art. Cubiti, the muscles of the forearm; Wound Care skill. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 29 | Functional structure of junctions and the general principles of junction transmissions, specialized connective tissue: bone and cartilage, muscle tissue: smooth, striated and cardiac muscle, blood and lymph vessels of the upper extremity, columna vertebralis, vertebral joints, compound action potential, Anatomy Laboratory: Forearm and hand region, upper extremity nerves; Histology Laboratory: Supportive tissue: connective and fatty tissue, wound care skills. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 30 | Muscle tissue: smooth, striated and cardiac muscle, histology of nerve tissue, physiology of skeletal muscle and smooth muscle, Muscular contraction: biomechanical and bioenergetic relationships, bioelectric events in muscles and EMG, factors of columna vertebralis movement , femur joint, Anatomy Laboratory: Upper extremity vessels, columna vertebralis and vertebral joints; Histology laboratory: Tissue of bone and cartilage, wound care skills. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 31 | The muscles affecting femur joint, thigh region femoral triangle, adductor canal, knee joint, Histology of nerve tissue, Biomagnetism, Biophysics applications and Laboratory, Laboratory of Anatomy: The femur joint and gluteal region, thigh region femoral triangle, adductor canal; Histology laboratory: Muscle and nerve tissue. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 32 | Leg, Ankle and the muscles affecting foot movements, blood vessels of lower extremity and lymphatics, nerve lesions and nerves, Biophysics applications and laboratory, Anatomy Laboratory: Leg, Ankle and foot. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 33 | Skin and side formations, walking and posture, Integrated Session, Histology Laboratory: Skin and adverse occurrences; Anatomy Laboratory: Ankle and the muscles affecting foot movements, blood vessels of lower extremity and lymphatics, nerves of lower extremity. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 34 | IV. Term Written Examination Committee | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav |
| 35 | Cancer genetics, Peripheral blood, myeloid organs, Hematopoiesis and hemotopoietic organs, Blood formation, erythrocytes, erythropoiesis, functions of white blood cells, relations with host and microorganism, Introduction to Immunology, Bone: The mechanical and electrical properties, erythrocyte metabolism, Anatomy laboratory: the bones of the skull; Histology laboratory: Peripheral blood, myeloid organs. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 36 | The development of the immune system, humoral immunity, Apoptosis, Biomagnetism, as a social institution and as an applied science of medicine: Medicine and Law; hemoglobin structure, synthesis and evolution, structure of myoglobin, hemoglobin degradation, antigens and microbial antigens, Facial anatomy, Head and neck vessels, lymphatics and nerves, Histology laboratory: Hematopoiesis and hemotopoietic organs; Anatomy laboratory: neck and face. | Preparatory work for the course | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 34 | 20 | 680 |
| Out of Class Study (Preliminary Work, Practice) | 10 | 2 | 20 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 6 | 12 | 72 |
| Mid-term Exams (Written, Oral, etc.) | 10 | 20 | 200 |
| Final Exam | 4 | 8 | 32 |
| Total Workload (Hour) | 1004 | ||
| Total Workload / 25 (h) | 40,16 | ||
| ECTS | 40 ECTS | ||