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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| VETERINARY PHARMACOLOGY AND TOXICOLOGY (MASTER) (WITH THESIS) | |
| Code | VFT501 |
| Name | General Toxicology |
| Term | 2024-2025 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
Prof. Dr. Oğuzhan YAVUZ
(Güz)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
The course aims to teach poisoning events in animals, agents that may cause poisoning, poison groups, and treatment approaches in poisoning.
Course Content
The content of this course consists of basic concepts related to toxicology, properties of toxic substances, toxicity types and tests, factors affecting toxicity, changes of poisons in the body, general diagnosis and treatment of poisonings.
Course Precondition
There are no prerequisites for this course.
Resources
Kaya S. (Ed). 2002, Veteriner Hekimliğinde Toksikoloji, Medisan Yayınevi, ISBN: 975-7774-50-2 Ateşşahin A., Servi K. 2017. Veteriner Hekimler İçin Klinik Toksikoloji, Medipres, ISBN: 978-605-9720-12-0.
Notes
Lecture notes and presentations.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Defines toxicology and its aims |
| LO02 | Describes the importance of toxicology, its sub-branches, and the concepts of poison and intoxication. |
| LO03 | Classifies toxic substances |
| LO04 | Explains the types of poisoning, the effects of poisons and the interactions between poisons. |
| LO05 | Explains toxicity and toxicity tests. |
| LO06 | Explains the dose-concentration and dose-effect relationship. |
| LO07 | Lists the factors affecting toxicity. |
| LO08 | Interprets on the principles of toxicokinetics |
| LO09 | Explains the mode of actions of poisons. |
| LO10 | Explains the causes, diagnosis and treatment of poisonings. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explains the sources, properties, and effects of drugs, the situations in which they are used and not used, their movements in the body, their interactions with other drugs, and the conditions of use in livestock animals. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Explains the properties of toxic substances, their sources, toxicity, movements in the body, modes of action, effects, methods of diagnosis, treatment, and protection. | 5 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the doses and forms of drugs used in treatment. | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Explains the administration and exposure routes of drugs and poisons and their changes in the animal body. | 5 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Explains the mechanisms of action of drugs and poisons in the body. | 5 |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Prepares basic drug formulations in the laboratory. | |
| PLO07 | Bilgi - Kuramsal, Olgusal | Explains the analytical methods and devices used in pharmacology and toxicology. | |
| PLO08 | Yetkinlikler - Alana Özgü Yetkinlik | Can report and interpret the results obtained from pharmacological and toxicological analyses | |
| PLO09 | Yetkinlikler - Alana Özgü Yetkinlik | Explains and applies the ethical rules that must be followed with experimental animals and alternative methods used in scientific researches. | 4 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Explains the harmful effects of chemical, biological, radiological, and nuclear warfare agents on human, animal, and environmental health and applies protection methods against these agents. | 2 |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Follows and evaluates current information, methods, and practices related to Veterinary Pharmacology and Toxicology and can use them in the scientific works. | 5 |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Prepares, publishes, and presents articles using the results of scientific studies in Veterinary Pharmacology and Toxicology. | |
| PLO13 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Can manage and participate in scientific research projects in Veterinary Pharmacology and Toxicology. | |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Participates in commissions that deal with the identification and solution of problems related to human, animal, and environmental health using the knowledge gained in Veterinary Pharmacology and Toxicology | |
| PLO15 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Can carry out joint research projects with branches of science related to pharmacology and toxicology. | |
| PLO16 | Beceriler - Bilişsel, Uygulamalı | Plans scientific studies based on the priority areas of the Council of Higher Education and the university and sustainable development goals and adopts lifelong learning as a principle. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | History, Definition and Importance of Toxicology, Sub-Disciplines of Toxicology | Examining lecture notes | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Anlatım |
| 2 | Concepts of Poison and Poisoning, Classification of Toxic Substances, Special Groups Found in Toxic Substances | Examining lecture notes and textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Bireysel Çalışma |
| 3 | Types of Poisoning and Effects of Poisons, Interactions Between Poisons | Examining lecture notes | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Poisoning and Toxicity Tests, Translation of Animal Trial Results to Humans | Doing research on Ethics Committees | Öğretim Yöntemleri: Anlatım, Bireysel Çalışma |
| 5 | Dose and ConcentrationRelationship, Dose and Effect Relationship | Examining lecture notes | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Factors Affecting Toxicity | Examining lecture notes | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Ways of Entry of Poisons into the Body and Absorption, Distribution and Accumulation | Review related literature | Öğretim Yöntemleri: Anlatım, Bireysel Çalışma |
| 8 | Mid-Term Exam | Exam study | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav, Ödev |
| 9 | Changes of Poisons in the Body and Excretion | Investigation of kidney function tests | Öğretim Yöntemleri: Anlatım, Bireysel Çalışma, Problem Çözme |
| 10 | Effect of Gastrointestinal Microflora on Toxic Substances | Examination of digestive system notes | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Bireysel Çalışma |
| 11 | Kinetic Calculations | Research on pharmacokinetic programs | Öğretim Yöntemleri: Anlatım, Bireysel Çalışma, Problem Çözme |
| 12 | Modes of Action of Poisons | Examining lecture notes | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Causes of Poisoning | Examining sample cases | Öğretim Yöntemleri: Örnek Olay, Bireysel Çalışma |
| 14 | Diagnosis and Treatment of Poisoning | Examining sample cases | Öğretim Yöntemleri: Örnek Olay, Bireysel Çalışma, Problem Çözme |
| 15 | Main Antidotes Used in the Treatment of Poisonings | Research on commercial antidote preparations for veterinary and human use | Öğretim Yöntemleri: Örnek Olay, Bireysel Çalışma |
| 16 | Term Exams | Exam study | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav, Ödev |
| 17 | Term Exams | Exam study | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav, Ödev |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Midterm Exam | 100 | 40 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 15 | 3 | 45 |
| Out of Class Study (Preliminary Work, Practice) | 17 | 2 | 34 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 48 | 48 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 15 | 15 |
| Total Workload (Hour) | 150 | ||
| Total Workload / 25 (h) | 6,00 | ||
| ECTS | 6 ECTS | ||