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Information
| Unit | INSTITUTE OF NATURAL AND APPLIED SCIENCES |
| BIOTECHNOLOGY (MASTER) (WITH THESIS) (INTERDISCIPLINARY) | |
| Code | BT0163 |
| Name | Free Radical Biology |
| Term | 2024-2025 Academic Year |
| Term | Fall |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
Prof. Dr. HİKMET YETER ÇOĞUN
(Güz)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Understanding free radical chemistry and antioxidant defense
Course Content
Introduction to oxygen toxicity and reactive oxygen species. Chemistry of free radicals and associated reactive species. Antioxidant defenses. Oxidative stress. Determination of free radicals and other reactive species
Course Precondition
Being a graduate of the Department of Biology, Faculty of Veterinary Medicine, Food Engineering, Fisheries.
Resources
Halliwell, B., & Gutteridge, J. M. (2015). Free radicals in biology and medicine. Oxford university press, USA.
Notes
-Lecture notes -Pryor, W. (Ed.). (2012). Free Radicals in Biology V6 (Vol. 6). Elsevier.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explain antioxidants and their mechanisms. |
| LO02 | Describes cell damage and its methods |
| LO03 | Explain the structural changes that occur in a damaged cell. |
| LO04 | Designs the examination of scientific research on the subject and the presentation of articles. |
| LO05 | Defines free radicals in living things |
| LO06 | Designs the effects of antioxidants and species |
| LO07 | Explains oxygen toxicity |
| LO08 | Identifies free radicals in cellular mechanisms |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on undergraduate level qualifications, they develop their knowledge at the level of expertise in the same or a different field. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Knows the ethical rules to be considered while obtaining biotechnological products. | 4 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | To identifiy the interdisciplinary interaction of the field and to solve use of the methods. | 5 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Interpret the knowledge gained in the field by integrating the information from different disciplines and creates new information | |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Develops new strategic approaches for solving complex problems that are encountered in applications related to the field. | |
| PLO06 | Yetkinlikler - Öğrenme Yetkinliği | To teach the social, scientific, cultural and ethical values during the collection, interpretation, implementation and announcement of the data related to the field. | 2 |
| PLO07 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | To solve the problems encountered in the field and cominicate by using research methods. | |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Establishes functional interaction by using strategic decision-making processes in solving the problems encountered in the field. | |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. | |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | To gain the ability to develop and deepen the knowledge in the field of biotechnology | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Free radicals in living systems | Lecture notes | Öğretim Yöntemleri: Anlatım |
| 2 | oxygen toxicity | Course Notes and Books | Öğretim Yöntemleri: Anlatım |
| 3 | Free radical behavior | Lecture notes | Öğretim Yöntemleri: Soru-Cevap |
| 4 | antioxidants | Other Resources | Öğretim Yöntemleri: Anlatım |
| 5 | Enzymatic and non-enzymatic types of antioxidants | Lecture notes | Öğretim Yöntemleri: Anlatım |
| 6 | Antioxidant defense: general principles | Internet research | Öğretim Yöntemleri: Soru-Cevap |
| 7 | Specific roles of free radicals in the cell | Reading current sources | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Exam preparation | Ölçme Yöntemleri: Sözlü Sınav, Ödev |
| 9 | Introduction to oxygen toxicity and reactive species | Lecture notes | Öğretim Yöntemleri: Anlatım |
| 10 | Molecular behavior of free radicals | Reading current sources | Öğretim Yöntemleri: Soru-Cevap |
| 11 | Structure of antioxidants | Lecture notes | Öğretim Yöntemleri: Anlatım |
| 12 | Antioxidant types: possible effects of enzymatic and non-enzymatic types in vivo | Other Resources | Öğretim Yöntemleri: Anlatım |
| 13 | Antioxidant defense and live | Internet research | Öğretim Yöntemleri: Soru-Cevap |
| 14 | Molecular structure of free radicals | Lecture notes | Öğretim Yöntemleri: Anlatım |
| 15 | Oxygen toxicity and cell damage by reactive species | Reading a textbook | Öğretim Yöntemleri: Anlatım |
| 16 | Term exams | Exam preparation | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
| 17 | Term Exams | Exam preparation | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Midterm Exam | 100 | 40 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 12 | 3 | 36 |
| Out of Class Study (Preliminary Work, Practice) | 15 | 5 | 75 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 3 | 3 | 9 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 15 | 15 |
| Total Workload (Hour) | 150 | ||
| Total Workload / 25 (h) | 6,00 | ||
| ECTS | 6 ECTS | ||