TÜRKÇE
ENGLISH
Information
| Code | BTE0015 |
| Name | Applications of bioinformatics-I |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 3-2 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 4 National Credit |
| Teaching Language | İngilizce |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator |
Course Goal / Objective
Main purpose of this course is to give students an insight on bioinformatics utilization in molecular genetic testing
Course Content
In this course, genetic changes on nucleic acids will be analyzed and the effects of this mutations on protein level will be examined in the light of bioinformatic tools and databases.
Course Precondition
none
Resources
Bioinformtics related on Articles
Notes
Bioinformtics related on Articles/Books
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Having an information about bioinformatics |
| LO02 | Having an information about bioinformatics application fields |
| LO03 | Understangind the relation between molecular genetic testing and bioinformatics |
| LO04 | Recognition of bioinformatics tools and databases |
| LO05 | Being able to evaluate variants |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develop and deepen the current and advanced knowledge in the field with original thought and / or research at the level of expertise based on the qualifications of the graduate and reach the original definitions that will bring innovation to the field. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Understands the interdisciplinary interaction of the field; it achieves original results using knowledge requiring expertise in analysis, synthesis and evaluation of new and complex ideas. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Evaluates, uses and transfers new information in the field with a systematic approach. | 3 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Makes critical analysis, synthesis and evaluation of new and complex thoughts. | 3 |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Makes leadership in environments that require the analysis of original and interdisciplinary problems. | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | It extends the limits of knowledge in its field by publishing at least one scientific article in its field in national and / or international refereed journals and / or producing or interpreting an original work. | |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. | |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. | |
| PLO09 | Yetkinlikler - Alana Özgü Yetkinlik | Conducts scientific research in national and international scientific research groups. | |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | Establishes functional interaction by using strategic decision making processes in solving problems encountered in the field. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to bioinformatics | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 2 | Basics of clinical applications of bioinformatics | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 3 | Bioinformatics in molecular genetics | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 4 | Overview of the bioinformatics solutions on the medical market | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Bioinformatics in sequencing | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Tartışma |
| 6 | Introduction to Next Generation Sequencing | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 7 | Next Generation Sequencing systems | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 8 | Mid-Term Exam | No need for preliminary preparation | Ölçme Yöntemleri: Ödev |
| 9 | Next Generation Sequencing application | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 10 | Setting Up Your NGS Analysis Pipeline | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama, Gösterip Yaptırma |
| 11 | Quality Assessment of NGS Data | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 12 | Bioinformatics Application 1 | No need for preliminary preparation | Öğretim Yöntemleri: Alıştırma ve Uygulama, Gösterip Yaptırma |
| 13 | Bioinformatics Application 2 | No need for preliminary preparation | Öğretim Yöntemleri: Alıştırma ve Uygulama, Gösterip Yaptırma |
| 14 | The tools, databases and guidelines required for variant interpretation | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 15 | The tools, databases and guidelines required for variant interpretation-2 | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 16 | Term Exams | No need for preliminary preparation | Ölçme Yöntemleri: Ödev |
| 17 | Term Exams | No need for preliminary preparation | Ölçme Yöntemleri: Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 5 | 70 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 5 | 5 |
| Final Exam | 1 | 15 | 15 |
| Total Workload (Hour) | 160 | ||
| Total Workload / 25 (h) | 6,40 | ||
| ECTS | 6 ECTS | ||