TÜRKÇE
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Information
| Code | EFR505 |
| Name | In vivo and In vitro Drug Studies |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator |
Course Goal / Objective
Learns the general characteristics of experimental animals and gain the ability to administer drugs, have knowledge about in vitro and in vivo experimental protocols.Gains the ability to distinguish the differences between in vitro and in vivo studies. Gains the ability to solve problems that may arise in experiments.
Course Content
Basic information about experimental pharmacology and general methodology , In vitro and in vivo study methods and recording systems
Course Precondition
None
Resources
1- Kayaalp S. Oğuz. Medical Pharmacology in Terms of Rational Treatment, volume 1 and 2, Pelikan Publications,2019. 2- Jann Hau, Gerald L Van Hoosier, Animal models in pharmacology and toxicology. In: Handbook of laboratory animal science. 2nd edition CRC Press, 2003. 3-Bökesoy T.Arda. Isolated smooth muscle preparations, Turkish Pharmacology Society Publications,1993. 4-Current Literatures.
Notes
lecture notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Gains the skill of using laboratory materials. |
| LO02 | Explains and compares the methods used in experimental research. |
| LO03 | Explains in vitro and in vivo research methods. |
| LO04 | Gains the ability to solve problems that may arise in experiments |
| LO05 | Gains the ability to collect experimental data and evaluate the results. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explain the mechanisms of action of drugs, their pharmacokinetic and pharmacodynamic effects. | 2 |
| PLO02 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Acts in accordance with ethical and legal principles in the field of pharmacology. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Can project and conduct research in the field of pharmacology and analyze and interpret data. | 4 |
| PLO04 | Yetkinlikler - Alana Özgü Yetkinlik | It plays an active role in rational drug use and provides counseling to the patient for the correct use of the drug. | |
| PLO05 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Can convey the current developments or studies in the field of pharmacology verbally or in writing. | 3 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Follows scientific literature and current developments in the field of pharmacology. | 4 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Establishes a relationship between the effects, mechanisms of action and drug interactions of drugs. | |
| PLO08 | Bilgi - Kuramsal, Olgusal | Explain the physiopathology of various diseases and evalue the drugs used in the treatment of these diseases. | |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Knows and uses good laboratory practices. | 5 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Uses the theoretical and applied knowledge gained in the field of pharmacology. | 4 |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Have the ability to take part in in vitro/in vivo animal studies. | 5 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Explaining the Importance of the Course, Its Operation and Evaluation Method to the Student. Explaining the Importance of the Course | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Explanation of Uses of Laboratory Materials | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösteri |
| 3 | Animal Models Used in Experimental Research: Hypertension, Cystitis, Diabetes | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | Preclinical Experimental Studies: In vitro organ bath experiments | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar |
| 5 | In Vitro Organ Bath Assembly and Recording Systems (Isometric and Isotonic Transducer) | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 6 | What are the physiological solutions used in in vitro organ bath experiments and their importance | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Dose Calculation in In Vitro Studies | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | Subject repetition | Ölçme Yöntemleri: Sözlü Sınav, Performans Değerlendirmesi |
| 9 | Drug Administration to Experimental Animals | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 10 | In Vivo Study Methods, Drug Administration Routes and Calculation of the Drug Dose to be administered | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 11 | Calculation of Drug Dose to be Administered In Vivo | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | In Vivo Registration System | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | In Vivo Experiment Model-1 | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | In Vivo Experiment Model-2 | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | Analysis and Interpretation of Data | Reading related books and literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 16 | Term Exam | General Review | Ölçme Yöntemleri: Ödev, Performans Değerlendirmesi |
| 17 | Term Exams | General Review | Ölçme Yöntemleri: Ödev, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 7 | 7 |
| Final Exam | 1 | 18 | 18 |
| Total Workload (Hour) | 109 | ||
| Total Workload / 25 (h) | 4,36 | ||
| ECTS | 4 ECTS | ||