EFR505 In vivo and In vitro Drug Studies

4 ECTS - 3-0 Duration (T+A)- . Semester- 3 National Credit

Information

Code EFR505
Name In vivo and In vitro Drug Studies
Term 2024-2025 Academic Year
Semester . Semester
Duration (T+A) 3-0 (T-A) (17 Week)
ECTS 4 ECTS
National Credit 3 National Credit
Teaching Language Türkçe
Level Yüksek Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator


Course Goal / Objective

Learns the general characteristics of experimental animals and gain the ability to administer drugs, have knowledge about in vitro and in vivo experimental protocols.Gains the ability to distinguish the differences between in vitro and in vivo studies. Gains the ability to solve problems that may arise in experiments.

Course Content

Basic information about experimental pharmacology and general methodology , In vitro and in vivo study methods and recording systems

Course Precondition

None

Resources

1- Kayaalp S. Oğuz. Medical Pharmacology in Terms of Rational Treatment, volume 1 and 2, Pelikan Publications,2019. 2- Jann Hau, Gerald L Van Hoosier, Animal models in pharmacology and toxicology. In: Handbook of laboratory animal science. 2nd edition CRC Press, 2003. 3-Bökesoy T.Arda. Isolated smooth muscle preparations, Turkish Pharmacology Society Publications,1993. 4-Current Literatures.

Notes

lecture notes


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Gains the skill of using laboratory materials.
LO02 Explains and compares the methods used in experimental research.
LO03 Explains in vitro and in vivo research methods.
LO04 Gains the ability to solve problems that may arise in experiments
LO05 Gains the ability to collect experimental data and evaluate the results.


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal Explain the mechanisms of action of drugs, their pharmacokinetic and pharmacodynamic effects. 2
PLO02 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Acts in accordance with ethical and legal principles in the field of pharmacology.
PLO03 Beceriler - Bilişsel, Uygulamalı Can project and conduct research in the field of pharmacology and analyze and interpret data. 4
PLO04 Yetkinlikler - Alana Özgü Yetkinlik It plays an active role in rational drug use and provides counseling to the patient for the correct use of the drug.
PLO05 Yetkinlikler - İletişim ve Sosyal Yetkinlik Can convey the current developments or studies in the field of pharmacology verbally or in writing. 3
PLO06 Bilgi - Kuramsal, Olgusal Follows scientific literature and current developments in the field of pharmacology. 4
PLO07 Bilgi - Kuramsal, Olgusal Establishes a relationship between the effects, mechanisms of action and drug interactions of drugs.
PLO08 Bilgi - Kuramsal, Olgusal Explain the physiopathology of various diseases and evalue the drugs used in the treatment of these diseases.
PLO09 Beceriler - Bilişsel, Uygulamalı Knows and uses good laboratory practices. 5
PLO10 Beceriler - Bilişsel, Uygulamalı Uses the theoretical and applied knowledge gained in the field of pharmacology. 4
PLO11 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Have the ability to take part in in vitro/in vivo animal studies. 5


Week Plan

Week Topic Preparation Methods
1 Explaining the Importance of the Course, Its Operation and Evaluation Method to the Student. Explaining the Importance of the Course Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
2 Explanation of Uses of Laboratory Materials Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Gösteri
3 Animal Models Used in Experimental Research: Hypertension, Cystitis, Diabetes Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
4 Preclinical Experimental Studies: In vitro organ bath experiments Reading related books and literature Öğretim Yöntemleri:
Anlatım, Deney / Laboratuvar
5 In Vitro Organ Bath Assembly and Recording Systems (Isometric and Isotonic Transducer) Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Deney / Laboratuvar
6 What are the physiological solutions used in in vitro organ bath experiments and their importance Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
7 Dose Calculation in In Vitro Studies Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
8 Mid-Term Exam Subject repetition Ölçme Yöntemleri:
Sözlü Sınav, Performans Değerlendirmesi
9 Drug Administration to Experimental Animals Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Deney / Laboratuvar
10 In Vivo Study Methods, Drug Administration Routes and Calculation of the Drug Dose to be administered Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
11 Calculation of Drug Dose to be Administered In Vivo Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
12 In Vivo Registration System Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
13 In Vivo Experiment Model-1 Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
14 In Vivo Experiment Model-2 Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
15 Analysis and Interpretation of Data Reading related books and literature Öğretim Yöntemleri:
Anlatım, Soru-Cevap
16 Term Exam General Review Ölçme Yöntemleri:
Ödev, Performans Değerlendirmesi
17 Term Exams General Review Ölçme Yöntemleri:
Ödev, Performans Değerlendirmesi


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 3 42
Out of Class Study (Preliminary Work, Practice) 14 3 42
Assesment Related Works
Homeworks, Projects, Others 0 0 0
Mid-term Exams (Written, Oral, etc.) 1 7 7
Final Exam 1 18 18
Total Workload (Hour) 109
Total Workload / 25 (h) 4,36
ECTS 4 ECTS

Update Time: 17.05.2024 08:27