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Information
| Code | HİS516 |
| Name | Stem cell biology |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. SAİT POLAT |
Course Goal / Objective
Getting information about the main features of stem cells, cell cycles, cell differentiation and cell types
Course Content
Description of stem cell notion, basic features of stem cells, description of pluripotency, embryonic, adult and induced pluripotent stem cells
Course Precondition
none
Resources
Kök Hücre Biyolojisi, Türleri ve Tedavide Kullanımları Alp CAN Akademisyen Yayınevi
Notes
ders sunumları
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Defines stem cell notion. |
| LO02 | Knows basic properties of stem cells |
| LO03 | Knows pluripotency notion. |
| LO04 | Says self renewal and differentiation types of stem cells. |
| LO05 | Defines stem cell niche. 7.Says basic stem ce |
| LO06 | Be informed of cell cycle and aging of stem cells. |
| LO07 | Says basic stem cell types. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Tell the basic histological features of cells and tissues. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Can establish connection betwwen the structure and function of the cells. | 4 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Have knowledge about the histological properties of organ systems. | 4 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Have knowledge about embryo development, development disorders and mechanisms. | 4 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Define light and electron microscopic tissue preparation and examination methods. | 3 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Has knowledge about general principles of cell culture, histochemistry and immunohistochemistry. | 5 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Prepare tissues for light and electron microscopic analysis. | 3 |
| PLO08 | Bilgi - Kuramsal, Olgusal | Apply basic histochemical staining methods. | 4 |
| PLO09 | Bilgi - Kuramsal, Olgusal | Can distinguish tissue and organ systems at light microscopic level. | 3 |
| PLO10 | Bilgi - Kuramsal, Olgusal | He / she carries out his / her study as an individual or a team member. | |
| PLO11 | Bilgi - Kuramsal, Olgusal | Do the tasks given within the scope of research projects. | |
| PLO12 | Beceriler - Bilişsel, Uygulamalı | Develop a positive attitude and behavior related to lifelong learning. | |
| PLO13 | Beceriler - Bilişsel, Uygulamalı | Identifies learning needs and resources, and guides them by using resources effectively. | |
| PLO14 | Beceriler - Bilişsel, Uygulamalı | Evaluate the knowledge and skills at the graduate level with a critical approach. | |
| PLO15 | Beceriler - Bilişsel, Uygulamalı | Use information and communication technologies at the level required by the field. | |
| PLO16 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Communicate effectively. | |
| PLO17 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Transfer their ideas and solutions by quantitative and qualitative datas by supporting the current developments and their studies orally and visiually | |
| PLO18 | Yetkinlikler - Öğrenme Yetkinliği | Knows the importance of ethical principles in conducting research studies, evaluating and sharing the results. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Definition and terminology of stem cells. | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 2 | Pluripotency notion, external factors of pluripotency. | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 3 | Internal factors of pluripotency; Oct-4, Nanog, Sox-2 transcription factors | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 4 | Differantiation types of stem cells and the epigenetic control of the differentiation. | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 5 | Stem cell niche: intestinal mucosa niches and hemopoietic stem cell niche. | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 6 | The self renewal features of stem cells, cell cycle. | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 7 | Protection of genom integrity in stem cells and stress | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 9 | Stem cell aging | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 10 | Embriyonic stem cells and in-vitro differentiation perfections. | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 11 | Epiblast stem cells and embryonic carsinoma cells. | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 12 | Multipotent stem cells; neural crest-derived stem cells. | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 13 | Amnion, placenta and umblical cord- derived stem cells. | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 14 | Adult stem cells | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 15 | Presentation article and discussion about the subject | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 16 | Term Exams | Self-study, reading recommended references | Öğretim Yöntemleri: Anlatım |
| 17 | Term Exams | Ölçme Yöntemleri: Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 24 | 24 |
| Total Workload (Hour) | 88 | ||
| Total Workload / 25 (h) | 3,52 | ||
| ECTS | 4 ECTS | ||