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Information
| Code | VET243 |
| Name | Genetics and Molecular Biology |
| Term | 2024-2025 Academic Year |
| Semester | 3. Semester |
| Duration (T+A) | 1-1 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 1 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | FE Field Education Courses C Compulsory |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. TÜLİN GÜVEN GÖKMEN |
| Course Instructor |
Doç. Dr. TÜLİN GÜVEN GÖKMEN
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
It aims to learn how the differences between the living things of the students arise from what they are, the genotypic effect of these differences, how the genetic information is transferred from one generation to the next, the definition and structure of genes, intergenerational interactions, genotype x environment interactions, hereditary diseases, hereditary diseases, mutations, and general principles in molecular biology, DNA and RNA constructs and functions, transcription and translation mechanisms, cloning with recombinant DNA technologies and gene expression and molecular biology methods.
Course Content
The source of the differences among living things, genotype, phenotype, transfer of genetic information from front to back, DNA and RNA structures and functions, polymerase chain reaction, transcription and translation processes, cloning with recombinant DNA technologies and gene expressions, interactions between genes, genotype x environment interactions, hereditary diseases, hereditary diseases, mutation, population genetics
Course Precondition
There is no prerequisite.
Resources
Lecture Notes Veterinary Genetic: Prof. Dr. Bilal Akyüz , Prof. Dr. Akın Yakan et al. Basic Veterinary Genetic: PROF.DR.OKAN ERTUĞRUL
Notes
Visual resources
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Defines the basic concepts of genetics. |
| LO02 | Explains the structures of DNA, RNA molecules. |
| LO03 | Explains the processes of replication, transcription and translation. |
| LO04 | Lists molecular techniques that can be applied in areas such as infectious diseases, hereditary diseases and food analysis in veterinary medicine. |
| LO05 | Explains which polymorphisms or gene interactions exist in various hereditary diseases or phenotypes. |
| LO06 | Determines how to use genetic structure and which tests to choose in race determination, parenting tests and similar areas. |
| LO07 | Explains molecular genetic methods such as hybridoma technology used in veterinary medicine, cloning, stem cells, transgenic animals, embryo transfer, poly and monoclonal antibody production, DNA damage detection. |
| LO08 | Interprets the Hardy Weinberg hypothesis in population genetics |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Distinguishes animal species and breeds based on their structural (morphological), functional (physiological, biochemical) and behavioral characteristics and whether they can be consumed for food purposes. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Explains the sources, physical and chemical properties and preparation of drugs. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Describes the effects and side effects of medications on patients | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Explains the formation mechanisms of animal diseases and their pathological effects on the body. | |
| PLO05 | Bilgi - Kuramsal, Olgusal | It makes efficiency evaluations among animal breeds and, when necessary, carries out selection, hybridization and artificial insemination at a level that can carry out breeding work. | |
| PLO06 | Bilgi - Kuramsal, Olgusal | Disposes of dead animal material, tissue samples, medical and chemical waste appropriately in accordance with international, national laws and regulations. | 5 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | It determines the correct approach area for the patient by evaluating the examination, operation etc. practices in the clinic according to the topographic anatomy. | 3 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Uses biochemical parameters in diagnostic processes by evaluating the information obtained with cause-effect relationships. | |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Writes prescriptions in accordance with diagnosis and treatment protocols for diseases and poisoning in animals. | 2 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Implements necessary measures, including biosecurity, to control infectious diseases. | |
| PLO11 | Beceriler - Bilişsel, Uygulamalı | Performs necropsy to evaluate findings in dead animals, directs tissues to the necessary laboratory according to appropriate storage methods and prepares a report. | |
| PLO12 | Beceriler - Bilişsel, Uygulamalı | Monitors patients in the post-operative process according to the main treatment methods of surgical diseases in animal species. | |
| PLO13 | Beceriler - Bilişsel, Uygulamalı | Applies sedation, anesthesia and pain management methods safely according to animal species. | |
| PLO14 | Beceriler - Bilişsel, Uygulamalı | Correctly applies biosafety principles such as sterilization of clinical and laboratory equipment and clothing. | 3 |
| PLO15 | Beceriler - Bilişsel, Uygulamalı | It regulates the care and feeding protocols according to animal species and supervises the consumption of animal foods produced for human consumption or foods containing animal products in their composition. | |
| PLO16 | Beceriler - Bilişsel, Uygulamalı | Evaluates laboratory results of animal diseases and applies correct diagnosis, prognosis and treatment methods based on the data obtained. | 3 |
| PLO17 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | He/she is conscious of performing his/her profession by being aware of his/her powers and responsibilities. | |
| PLO18 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Examines scientific techniques and methods according to facts related to veterinary services and takes analysis or methodological responsibility for problems. | 3 |
| PLO19 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | It uses adequate technology in the hygienic production, manufacturing, processing, consumption and sales of food by conducting health control of animal food products produced for human consumption. | |
| PLO20 | Yetkinlikler - Öğrenme Yetkinliği | Lists the methods of producing and using scientific knowledge in his/her professional field. | |
| PLO21 | Yetkinlikler - Öğrenme Yetkinliği | Uses updated legislation regarding veterinary services when necessary. | |
| PLO22 | Yetkinlikler - Öğrenme Yetkinliği | Performs an examination appropriate to the case, applying the contribution of imaging methods to diagnosis and radiation safety in accordance with current regulations. | |
| PLO23 | Yetkinlikler - Öğrenme Yetkinliği | Keeps clinical and patient records using proper and scientific methods. | |
| PLO24 | Yetkinlikler - Öğrenme Yetkinliği | By observing the basic principles of medicine, it develops management methods and appropriate management plans for animal production enterprises. | |
| PLO25 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Implement social projects and plans with social awareness, based on professional skills and authority with a computer usage license, advanced computer software. | 3 |
| PLO26 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Works in cooperation with other colleagues by following the world agenda within the framework of professional ethics and deontology rules. | |
| PLO27 | Yetkinlikler - Alana Özgü Yetkinlik | Produces solutions to field-specific problems in line with scientific data/evidence. | |
| PLO28 | Yetkinlikler - Alana Özgü Yetkinlik | He/she has the ethical values of the veterinary profession and defends these values. | |
| PLO29 | Yetkinlikler - Alana Özgü Yetkinlik | Takes appropriate precautions by clinically recognizing zoonosis and notifiable diseases. | |
| PLO30 | Yetkinlikler - Alana Özgü Yetkinlik | Determines the methods of diagnosis, prevention, treatment and operation of diseases in different animal species. | |
| PLO31 | Yetkinlikler - Alana Özgü Yetkinlik | In emergency cases, intervenes in all animals and applies first aid methods. | |
| PLO32 | Yetkinlikler - Alana Özgü Yetkinlik | Makes judgments on animal husbandry principles and breeding by assessing the physical condition, welfare and rearing conditions of domestic animals, communicating appropriately with animal owners and colleagues. | |
| PLO33 | Yetkinlikler - Alana Özgü Yetkinlik | Independently interprets articles and presentations published in other scientific fields related to Veterinary Medicine to maintain professional development and skills. | |
| PLO34 | Yetkinlikler - Alana Özgü Yetkinlik | When necessary, euthanizes animals using appropriate methods and respecting the feelings of animal owners. | |
| PLO35 | Yetkinlikler - Alana Özgü Yetkinlik | By mastering the concepts of occupational safety in terms of the workplace and the personnel working with it, they have the competence to apply and defend it. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Why genetic and molecular biology for veterinarians | Lectures note, Books | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Structural properties of genetic material, structure of DNA and RNA, organization of DNA and genome | Lecture notes, Books, Visual materials, Laboratory Preparation | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar |
| 3 | DNA replication, RNA transcription | Lecture notes, Books, Visual materials, Laboratory Preparation | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar |
| 4 | Control of gene expression in bacteria and mammalian cells, translation of mRNA into proteins, post-translational modifications | Lecture notes, Books, Visual materials | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Character, phenotype, genotype, environment, environment x genotype interaction, variyations | Lecture notes, Books, Visual materials | Öğretim Yöntemleri: Anlatım, Tartışma |
| 6 | Genetic variations and inheritance (dominant and ressesive inheritance, intermedia inheritance), independence of genes and gametes, test combinations (mono hybridism, dihibridus mutant, trihibridus mutant, poly hybridus mutant)formulas that can be useful in integrations | Lecture notes, Books, Visual materials | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 7 | Genetics and genetic code (structural genes, operator genes, regulatory genes, role of cytoplasm in heredity), genetics (cell morphology, cytoplasm, nucleus, chromatin), chromosomes (chromosomal morphology, chromosomal types, karyotypes, fine structure of chromosomes, giant chromosomes) cell protein synthesis) | Lecture notes, Books, Visual materials, Laboratory Preparation | Öğretim Yöntemleri: Anlatım, Tartışma, Deney / Laboratuvar |
| 8 | Mid-Term Exam | Exam preparing | Ölçme Yöntemleri: Sözlü Sınav |
| 9 | Genetic differences in cell division and division of genetic importance, crossing over | Lecture notes, Books, Visual materials, Laboratory Preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 10 | Genetic associations (cryptomeria, epistasis, involvement of a pair of two genes in the formation of a character, pleitropi, polymeri) | Lecture notes, Books, Visual materials | Öğretim Yöntemleri: Anlatım |
| 11 | Lethal genes, methods of combating lethal genes, sex-linked inheritance | Lecture notes, Books, Visual materials | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Immunogenetics (blood groups in domestic animals, techniques used in blood group studies, parenting tests, relation of blood groups to yields) | Lecture notes, Books, Visual materials, Laboratory Preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 13 | Recombinations (conjugation, transduction, transformation)Mutations (deficiency, deletion, inversion, duplication, translocation, euphly, monoploidy, polyploidy, gene mutations), change of chromosome number | Lecture notes, Books, Visual materials | Öğretim Yöntemleri: Anlatım, Tartışma |
| 14 | Molecular genetics, Polymerase chain reaction and its importance in the diagnosis of diseases, recombinant gene technology, Hybridoma technology, recombinant gene technology, poly and monoclonal antibody production, DNA damage detection | Lecture notes, Books, Visual materials | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | Population genetic | Lecture notes, Books, Visual materials | Öğretim Yöntemleri: Anlatım, Tartışma |
| 16 | Term Exams | exam preparing | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | exam preparing | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 1 | 14 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 1 | 1 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 44 | ||
| Total Workload / 25 (h) | 1,76 | ||
| ECTS | 2 ECTS | ||