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Information
| Code | VET243 |
| Name | Genetics and Molecular Biology |
| Term | 2024-2025 Academic Year |
| Semester | 3. Semester |
| Duration (T+A) | 1-1 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 1 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. TÜLİN GÜVEN GÖKMEN |
| Course Instructor |
Doç. Dr. TÜLİN GÜVEN GÖKMEN
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
It aims to learn how the differences between the living things of the students arise from what they are, the genotypic effect of these differences, how the genetic information is transferred from one generation to the next, the definition and structure of genes, intergenerational interactions, genotype x environment interactions, hereditary diseases, hereditary diseases, mutations, and general principles in molecular biology, DNA and RNA constructs and functions, transcription and translation mechanisms, cloning with recombinant DNA technologies and gene expression and molecular biology methods.
Course Content
The source of the differences among living things, genotype, phenotype, transfer of genetic information from front to back, DNA and RNA structures and functions, polymerase chain reaction, transcription and translation processes, cloning with recombinant DNA technologies and gene expressions, interactions between genes, genotype x environment interactions, hereditary diseases, hereditary diseases, mutation, population genetics
Course Precondition
There is no prerequisite.
Resources
Lecture Notes
Notes
Veterinary Genetic: Prof. Dr. Bilal Akyüz , Prof. Dr. Akın Yakan et al.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Defines the basic concepts of genetics. |
| LO02 | Explains the structures of DNA, RNA molecules. |
| LO03 | Explains the processes of replication, transcription and translation. |
| LO04 | Explains molecular techniques that can be applied in areas such as infectious diseases, hereditary diseases and food analysis in veterinary medicine. |
| LO05 | Describes the hereditary diseases that can be encountered in animal species. It explains which polymorphisms or gene interactions exist in various hereditary diseases or phenotypes. |
| LO06 | Learns how to use genetic structure and which tests to choose in race determination, parenting tests and similar areas. |
| LO07 | Comprehends molecular genetic methods such as hybridoma technology used in veterinary medicine, cloning, stem cells, transgenic animals, embryo transfer, poly and monoclonal antibody production, DNA damage detection. |
| LO08 | Explains the population genetics and hardy weinberg hypothesis |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Recognize animal species and breeds in terms of their morphological, functional (physiological, biochemical) and behavioral characteristics. | 3 |
| PLO02 | Beceriler - Bilişsel, Uygulamalı | Determines the correct approach area for the patients by evaluating the examination, operation etc. practices in the clinic according to the topographic anatomy. | |
| PLO03 | Yetkinlikler - Alana Özgü Yetkinlik | Produces solutions to field-specific problems in line with scientific data/evidence. | 4 |
| PLO04 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Based on his/her professional skills and authority, he/she implements social projects and plans with social awareness. | 4 |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Becomes conscious of performing his profession by being aware of his powers and responsibilities. | 5 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Learn the structures of living organisms, their components at the cellular level, and chemical processes in the body. | 3 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Learn to use biochemical processes in diagnostic processes by evaluating the information obtained with cause-effect relationships. | |
| PLO08 | Yetkinlikler - Alana Özgü Yetkinlik | Demonstrates the ability to possess and defend the ethical values of the veterinary profession. | 3 |
| PLO09 | Yetkinlikler - Öğrenme Yetkinliği | Understands the methods of producing and using scientific knowledge in his/her professional field. | 3 |
| PLO10 | Bilgi - Kuramsal, Olgusal | Knows the sources of drugs, their physical and chemical properties and preparation. | 2 |
| PLO11 | Bilgi - Kuramsal, Olgusal | Knows the effects and side effects of medications on patients. | 4 |
| PLO12 | Beceriler - Bilişsel, Uygulamalı | Prescribes and administers medications in accordance with legislation. | |
| PLO13 | Beceriler - Bilişsel, Uygulamalı | Applies the principles of diagnosis and general treatment of poisoning in animals. | 3 |
| PLO14 | Bilgi - Kuramsal, Olgusal | Learns general diagnosis and treatment protocols of animal diseases. | |
| PLO15 | Beceriler - Bilişsel, Uygulamalı | Applies necessary measures, including biosecurity, to control infectious diseases. | 2 |
| PLO16 | Yetkinlikler - Alana Özgü Yetkinlik | Clinically recognizes zoonotic and notifiable diseases and knows how to take appropriate precautions. | 4 |
| PLO17 | Beceriler - Bilişsel, Uygulamalı | Performs systematic necropsy on dead animals, evaluates the findings, knows the methods of preserving tissues and directs them to the necessary laboratories. | |
| PLO18 | Bilgi - Kuramsal, Olgusal | Knows the formation mechanisms of animal diseases and the pathological effects they cause in the body. | 3 |
| PLO19 | Yetkinlikler - Alana Özgü Yetkinlik | Determines the methods of diagnosis, prevention, treatment and operation of surgical diseases in different animal species. | 3 |
| PLO20 | Beceriler - Bilişsel, Uygulamalı | Uses the main treatment methods of surgical diseases in animal species. Evaluates and monitors patients in the postoperative period. | 2 |
| PLO21 | Beceriler - Bilişsel, Uygulamalı | Knows and applies sedation and anesthesia methods safely according to animal species. | 4 |
| PLO22 | Beceriler - Bilişsel, Uygulamalı | Knows and applies pain management methods. | 5 |
| PLO23 | Beceriler - Bilişsel, Uygulamalı | Correctly applies biosafety principles such as sterilization of clinical and laboratory equipment and clothing. | |
| PLO24 | Bilgi - Kuramsal, Olgusal | Applies the information about selection, hybridization and artificial insemination to be able to evaluate the productivity of animal breeds and to be able to carry out breeding work when necessary. | |
| PLO25 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Examines scientific techniques and methods according to facts related to veterinary services and takes analysis or methodological responsibility for problems. | |
| PLO26 | Yetkinlikler - Alana Özgü Yetkinlik | Determines clinical diagnosis and treatment protocols for diseases in different animal species. | |
| PLO27 | Yetkinlikler - Öğrenme Yetkinliği | Learns sufficient technological knowledge in the hygienic production, manufacturing, presentation for consumption and sales of animal foods produced for human consumption and/or foods containing animal products in their composition. | |
| PLO28 | Yetkinlikler - Alana Özgü Yetkinlik | Performs health checks on animal foodstuffs offered for consumption. | |
| PLO29 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Gains awareness about environmental and veterinary public health issues. | |
| PLO30 | Yetkinlikler - Öğrenme Yetkinliği | Follows updated legislation regarding veterinary services and uses it when necessary. | |
| PLO31 | Yetkinlikler - Öğrenme Yetkinliği | Knows the contribution of imaging methods in diagnosis. Performs an examination appropriate for the case by applying radiation safety according to current regulations. | |
| PLO32 | Yetkinlikler - Alana Özgü Yetkinlik | Treats all animals in emergency cases and applies first aid methods. | |
| PLO33 | Beceriler - Bilişsel, Uygulamalı | Prepares care and feeding protocols specific to animal species. | |
| PLO34 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Provides information to animal owners about breeding principles by evaluating the physical condition, welfare and rearing conditions of domestic animals. | |
| PLO35 | Yetkinlikler - Öğrenme Yetkinliği | Learns lifelong learning and training methods to maintain professional development and skills. | |
| PLO36 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Gains awareness of working in cooperation with other colleagues within the framework of professional ethics and deontology rules. | |
| PLO37 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Gains the ability to communicate effectively with patients, the community, colleagues and relevant authorities using appropriate language. | |
| PLO38 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Independently understand and interpret articles and presentations published in veterinary medicine and other related scientific fields. | |
| PLO39 | Yetkinlikler - Alana Özgü Yetkinlik | When necessary, euthanizes animals using appropriate methods and respecting the feelings of animal owners. | |
| PLO40 | Bilgi - Kuramsal, Olgusal | Learns how to properly dispose of dead animal material, tissue samples, medical and chemical waste. | |
| PLO41 | Beceriler - Bilişsel, Uygulamalı | Evaluates laboratory results of animal diseases and applies correct diagnosis, prognosis and treatment methods based on the data obtained. | |
| PLO42 | Yetkinlikler - Öğrenme Yetkinliği | Knows to keep clinical and patient records with proper and scientific methods. | |
| PLO43 | Yetkinlikler - Öğrenme Yetkinliği | Learns to prepare case and necropsy reports in a way that is understandable to the society and relevant institutions at a professional level when necessary. | |
| PLO44 | Yetkinlikler - Öğrenme Yetkinliği | Knows how to manage animal production businesses and make appropriate management plans, while taking into account basic medical principles. | |
| PLO45 | Yetkinlikler - Alana Özgü Yetkinlik | Understands the economic, sociocultural and emotional conditions in which veterinarians operate and positions themselves accordingly. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Why genetic and molecular biology for veterinarians | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Structural properties of genetic material, structure of DNA and RNA, organization of DNA and genome | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | DNA replication, RNA transcription | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Control of gene expression in bacteria and mammalian cells, translation of mRNA into proteins, post-translational modifications | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Character, phenotype, genotype, environment, environment x genotype interaction, variyations | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Genetic variations and inheritance (dominant and ressesive inheritance, intermedia inheritance), independence of genes and gametes, test combinations (mono hybridism, dihibridus mutant, trihibridus mutant, poly hybridus mutant)formulas that can be useful in integrations | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Genetics and genetic code (structural genes, operator genes, regulatory genes, role of cytoplasm in heredity), genetics (cell morphology, cytoplasm, nucleus, chromatin), chromosomes (chromosomal morphology, chromosomal types, karyotypes, fine structure of chromosomes, giant chromosomes) cell protein synthesis) | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Exam preparing | Ölçme Yöntemleri: Sözlü Sınav |
| 9 | Genetic differences in cell division and division of genetic importance, crossing over | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Genetic associations (cryptomeria, epistasis, involvement of a pair of two genes in the formation of a character, pleitropi, polymeri) | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Lethal genes, methods of combating lethal genes, sex-linked inheritance | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Immunogenetics (blood groups in domestic animals, techniques used in blood group studies, parenting tests, relation of blood groups to yields) | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Recombinations (conjugation, transduction, transformation) | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Mutations (deficiency, deletion, inversion, duplication, translocation, euphly, monoploidy, polyploidy, gene mutations), change of chromosome number | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Molecular genetics, Polymerase chain reaction and its importance in the diagnosis of diseases, recombinant gene technology, Hybridoma technology, recombinant gene technology, poly and monoclonal antibody production, DNA damage detection | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Population genetic | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 17 | Term Exams | exam preparingr | Ölçme Yöntemleri: Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 1 | 14 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 52 | ||
| Total Workload / 25 (h) | 2,08 | ||
| ECTS | 2 ECTS | ||