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Information
| Code | MEDF503 |
| Name | Radiobiology and Biophysics for Medical Physicists |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof.Dr. İSMAİL GÜNAY |
Course Goal / Objective
To teach the biological and ionizing radiation interactions, dose-response relationships in radiation effects with numerical examples
Course Content
Basic concepts of radiology, structure of atom, molecular bonds and bond energies, electromagnetic energy and ionization, human biology, basic principles of radiobiology, molecular radiobiology, cellular radiobiology, deterministic effects of radiation, stochastic effects of radiation, homework1,2,3,4, final exam
Course Precondition
The lesson has no prerequisites
Resources
Lecture notes (For Medical Faculty Students - İsmail Günay) Biophysics (Ferit Pehlivan) Biophysics (Gürbüz Çelebi)
Notes
Internet Search
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learns the types of radiation |
| LO02 | Discuss the effects of ionizing and non-ionizing radiations |
| LO03 | Know the importance of molecular bonds and bond energies |
| LO04 | Understands the basic principles of radiobiology |
| LO05 | Learn molecular radiobiology |
| LO06 | Understands the deterministic effects of radiation |
| LO07 | Understands the stochastic effects of radiation |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | List and explain the functions of health organizations; explains how national and international health institutions are organized; explains how clinics are managed. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Explains the technical infrastructure required for qualified service in the future of Medical Physics. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the European Community and national legal frameworks, regulations, guides and codes of practice related to the subject of Medical Physics. | 2 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Uses physical concepts, principles and theories in detail and numerically to explain structure, function, characteristics and limitations in fields covering Medical Physics; explains the use of medical devices in the field of medical physics. | 4 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Explains the properties of ionizing radiation (electromagnetic, electrons, ions, neutrons) and other physical agents (electric energy, static electricity/magnetic fields, non-ionizing electromagnetic radiation, vibration, sound and ultrasound, laser) in detail and quantitatively. | 3 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Explains the beneficial and adverse/harmful biological effects of ionizing radiation and different physical agents associated with medical devices numerically with biological models. Explain the factors affecting the magnitude of the biological effect. Explains ways of manipulation to improve clinical outcomes. | 2 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Explain deterministic/stochastic, early/late, teratogenic/genetic effects for each physical agent. | 3 |
| PLO08 | Bilgi - Kuramsal, Olgusal | Makes a list from the literature on General Physics, Medical Physics and Health Physics in order to systematically review something in the field of Medical Physics practice. | |
| PLO09 | Bilgi - Kuramsal, Olgusal | Applies the general concepts, principles and theories of physics to clinical problems related to the clinical use of medical devices, safety/risk management related to ionizing radiation. | 4 |
| PLO10 | Bilgi - Kuramsal, Olgusal | It uses the general concepts, principles and theories of physics to transfer new devices and related techniques to the clinical environment. | 3 |
| PLO11 | Bilgi - Kuramsal, Olgusal | It uses statistical packages for the analysis of clinical and biomedical data. | |
| PLO12 | Bilgi - Kuramsal, Olgusal | Defines and explains the various dosimetric quantities used; explains the relationship between dosimetric quantities (energy flux, kerma, absorbed dose). | 2 |
| PLO13 | Bilgi - Kuramsal, Olgusal | Designs clinical and biomedical studies that are numerical and based on a rigorous statistical base. | 3 |
| PLO14 | Bilgi - Kuramsal, Olgusal | Determines the method during the delivery of ionizing radiation to the patient and designs different applications to improve this method. | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Basic concepts of radiological science | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 2 | Structure of matter and Atom | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 3 | Molecular bonds and bond energies | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 4 | Electromagnetic energy and ionisation | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 5 | Human Biology | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 6 | Human Metabolism | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 7 | Basic principles of radiobiology | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Grup Çalışması, Beyin Fırtınası |
| 8 | Mid-Term Exam | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
| 9 | Molecular radiobiology | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 10 | Homework | Reads the relevant chapter before class | Öğretim Yöntemleri: Tartışma, Alıştırma ve Uygulama |
| 11 | Cellular radiobiology | Reads the relevant chapter before class | Öğretim Yöntemleri: Tartışma, Alıştırma ve Uygulama |
| 12 | Homework-1 | Reads the relevant chapter before class | Öğretim Yöntemleri: Tartışma, Alıştırma ve Uygulama |
| 13 | Deterministic effects of radiation | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 14 | Homework-2 | Reads the relevant chapter before class | Öğretim Yöntemleri: Tartışma, Alıştırma ve Uygulama |
| 15 | Stochastic effects of radiation | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 16 | Term Exams | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
| 17 | Term Exams | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 18 | 18 |
| Total Workload (Hour) | 114 | ||
| Total Workload / 25 (h) | 4,56 | ||
| ECTS | 5 ECTS | ||