TÜRKÇE
ENGLISH
Information
| Code | FAR546 |
| Name | |
| Term | 2024-2025 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
1 |
Course Goal / Objective
The aim of this course is to teach the basic concepts of ion channels.
Course Content
Ion channels - Introduction, Voltage-gated ion channels-I, Voltage-gated ion channels-II, Ligand-gated ion channels-I, Ligand-gated ion channels-II, Role of voltage-gated ion channels in the generation of electrical signals in neurons-I, Role of voltage-gated ion channels in the generation of electrical signals in neurons-II, Role of ligand-gated ion channels in the generation of electrical signals in neurons-I, The role of ligand-gated ion channels in the generation of electrical signals in neurons-II, Mechanisms of ligand binding, gating and ion selectivity, Structure-activity investigation methods of ion channels-I, Structure-activity investigation methods of ion channels-II, Contribution of changes in ion channel function to nervous system disorders-I, Contribution of changes in ion channel function to nervous system disorders-II
Course Precondition
Not required.
Resources
Scientific database
Notes
Scientific database
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Describes voltage-gated ion channels and ligand-gated ion channels. |
| LO02 | Refers to the role of voltage-gated ion channels and ligand-gated ion channels in the generation of electrical signals in neurons. |
| LO03 | Counts the methods of structure-activity investigation of ion channels. |
| LO04 | Explain the contribution of changes in ion channel function to nervous system disorders. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Ability to use the concepts of pharmacology, pharmacokinetics and pharmacodynamics | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Establishes relationships between drug effects, mechanisms of action, and drug interactions | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the side effects and toxic effects of drugs | |
| PLO04 | Yetkinlikler - Alana Özgü Yetkinlik | Uses an experimental setup for an in vitro or in vivo pharmacological study | |
| PLO05 | Bilgi - Kuramsal, Olgusal | Follows scientific literature related to his/her field | 5 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes part in the design, maintenance and analysis of data of a research related to his/her field. | |
| PLO07 | Bilgi - Kuramsal, Olgusal | Is aware of the importance of scientific research ethics. | 4 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Expresses scientific thought analytically and establishes hypotheses. | |
| PLO09 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes part in the statistical evaluation of data. | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Aware of the importance of rational drug use |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Ion channels - Introduction | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Voltage-gated ion channels-I | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Voltage-gated ion channels-II | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Ligand-gated ion channels-I | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Ligand-gated ion channels-II | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Role of voltage-gated ion channels in the generation of electrical signals in neurons-I | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Role of voltage-gated ion channels in the generation of electrical signals in neurons-II | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav |
|
| 9 | Role of ligand-gated ion channels in the generation of electrical signals in neurons-I | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Role of ligand-gated ion channels in the generation of electrical signals in neurons-II | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Mechanisms of ligand binding, gating and ion selectivity | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Structure-activity investigation methods of ion channels-I | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Structure-activity investigation methods of ion channels-II | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Contribution of changes in ion channel function to nervous system disorders-I | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Contribution of changes in ion channel function to nervous system disorders-II | books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 30 | 30 |
| Total Workload (Hour) | 101 | ||
| Total Workload / 25 (h) | 4,04 | ||
| ECTS | 4 ECTS | ||