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Information
| Code | FAR616 |
| Name | Toxicology |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. FATMA PEYMAN ERTUĞ |
Course Goal / Objective
The aim of the course is to teach the toxic effects of drugs, the basic concepts of toxicology, and drug allergic reactions.
Course Content
Simple and specific toxic effects, drug allergy, intolerance or hypersensitivity reactions, idiosyncrasy and reactions due to genetic variation, post-marketing investigation and evaluation of drug toxicity, experimental measurement of drug toxicity and therapeutic index
Course Precondition
There are no prerequisites for the course.
Resources
Medical pharmacology in terms of rational treatment Prof. Dr. S. Oğuz Kayaalp
Notes
Internet, library databases
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learn the toxic effects of drugs. |
| LO02 | Knows the basic concepts of toxicology. |
| LO03 | Know the classification of drug allergies. |
| LO04 | Provides information about the concept of teratogenicity and the classification of teratogenic effects. |
| LO05 | Explain the experimental measurement of drug toxicity and its therapeutic index. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Beceriler - Bilişsel, Uygulamalı | Discusses the mechanisms of action, side effects, and toxic effects of drugs. | 4 |
| PLO02 | Beceriler - Bilişsel, Uygulamalı | Explains drug effects, drug interactions and effects on organ systems with a systematic approach | 4 |
| PLO03 | Yetkinlikler - Alana Özgü Yetkinlik | Plans, implements and finalizes a scientific project | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Recognize the research areas and research techniques of pharmacology | |
| PLO05 | Yetkinlikler - Alana Özgü Yetkinlik | Comparatively examines and compiles scientific articles in the field of pharmacology. | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Prepares the experimental setup for an in vitro or in vivo pharmacological study and solves problems. | |
| PLO07 | Yetkinlikler - Alana Özgü Yetkinlik | He/she transforms the data obtained from the research project into a scientific research article. | |
| PLO08 | Yetkinlikler - Alana Özgü Yetkinlik | Evaluates drug use and its effects in society due to his/her knowledge about drugs. | 3 |
| PLO09 | Bilgi - Kuramsal, Olgusal | Explain clinical phase studies in drug development. | 2 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Evaluates and interprets study data statistically. | |
| PLO11 | Beceriler - Bilişsel, Uygulamalı | contributes to public health with its awareness of rational drug use. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Simple Toxic Effects | Pharmacology Textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 2 | Special Toxic Facilities | Pharmacology Textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Mutagenic (Genotoxic) Effect | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Carcinogenic (Oncogenic) effect (No chemical carcinogenesis) | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Teratogenic Effect | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Drug Allergy | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Type I (Anaphylactic) reactions | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Reading, repetition, research | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Type II (cytotoxic) reactions | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Type III (toxic immune complex deposition-related) reactions | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Type IV (delayed type) reactions | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Intolerance or hypersensitivity reactions | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Idiosyncrasy and reactions due to genetic differences | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Post-marketing investigation and evaluation of drug toxicity | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Experimental measurement of drug toxicity and therapeutic index | Reading, researching | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Reading, researching | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Reading, researching | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 18 | 18 |
| Total Workload (Hour) | 114 | ||
| Total Workload / 25 (h) | 4,56 | ||
| ECTS | 5 ECTS | ||