TÜRKÇE
ENGLISH
Information
| Code | Trans609 |
| Name | Biochemical Interaction of Biomolecules |
| Term | 2024-2025 Academic Year |
| Term | Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | İngilizce |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
Prof. Dr. ÖZLEM GÖRÜROĞLU ÖZTÜRK
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
to learn the physical, chemical and biological characteristics of biomolecules to understand which method can be used according to the characteristics of biomolecules
Course Content
Identification of specific biomolecules (carbohydrates, proteins, lipids, nucleic acids) for structural analysis the analytical methods which depends on physical, chemical and structural properties.
Course Precondition
Basic knowledge in biology, chemistry and biochemistry
Resources
Lehninger Principles of Biochemistry
Notes
Devlin Textbook of Biochemistry
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | to learn the physical, chemical and biological characteristics of biomolecules |
| LO02 | to understand which method can be used according to the characteristics of biomolecules |
| LO03 | to learn general principles of chromatography and chromatographic methods used for biomolecules. |
| LO04 | to learn general principles of mass spectrometry and methods used for biomolecules. |
| LO05 | to understand electrophoresis and capillary electrophoresis methods. |
| LO06 | to learn the basic principles of Flowcytometry |
| LO07 | to learn the basic principles of Molecular Methods |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develops and deepens the current and advanced level knowledge of translational medicine via unique thoughts or researches at a level of proficiency, find out original definitions that will bring innovation in the field of translational medicine. | 5 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Conceives the interdisciplinary interactions related to translational medicine; analyzes synthesizes and evaluates original and new thoughts. | 5 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the usage of tool, devices and instruments requiered for knowledge and technologies about translational medicine and its related disciplines. | 5 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Defines frequently used statistical methods in translational medicine and related disciplines, uses statistical softwares effectively. | |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Uses both theoretical and practical knowledge at an advanced level in the studies related to translational medicine. | |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Develops a new thoughts, method and designment/application which brings innovation in translational medicine or implements a known thoughts, method and designment/application in different fields, investigates, comprehends, designs, adapts, implements an original topic. | |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Writes the report of his/her research which he/she participated, | 3 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Makes necessary investigations by using tool, devices and instrument required for knowledge and technologies about translational medicine and related disciplines at an advanced level, develops a new and creative solution (device, method, treatment, drug) for the problems. | |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Uses statistical software in the field of Translational Medicine effectively, chooses statistical methods correctly, calculates and interprets correctly. | |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Maintains the organization of Translational Medicine laboratories and develops solutions in case of encountering unforeseen complex situations during laboratory working hours. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Conducts scientific studies in translational medicine and related fields independently or as a team member. | |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Writes the report of his/her research in which he/she participated, publishes in a national or international reputed journal (indexing in SCI, SCI-Expanded, SSCI, or AHCI), and presents it at scientific meetings. | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Follows evidence-based practices and conducts research on professional practices that will create evidence in their field. | 4 |
| PLO14 | Yetkinlikler - Öğrenme Yetkinliği | Applies the principles of advanced professional development and lifelong learning in the field of Translational Medicine. | |
| PLO15 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicate current developments and studies within the field to both professional and non-professional groups systematically using written, oral and visual techniques by supporting with quantitative and qualitative data. | |
| PLO16 | Bilgi - Kuramsal, Olgusal | Learns how to teach a concept, subject, phenomenon or case related to Translational Medicine. | |
| PLO17 | Belirsiz | Communicate and discuss orally, in written and visually with peers by using a foreign language at least at a level of European Language Portfolio B2 General Level. | |
| PLO18 | Yetkinlikler - Alana Özgü Yetkinlik | Audit the data gathering, interpretation, implementation and announcement stages by taking into consideration the cultural, scientific, and ethic values and uses these issues for social strategy, implementation plans and frame of quality processes. | |
| PLO19 | Yetkinlikler - Alana Özgü Yetkinlik | Knows the importance of ethical principles and ethical committees for the individual and society, acts ethically. | 5 |
| PLO20 | Yetkinlikler - Alana Özgü Yetkinlik | Increases the awareness of society about translational medicine. | 4 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Biyomoleküllerin fiziksel, kimyasal, yapısal özellikleri, biyolojik fonksiyonları 1 (carbohydrates) | Readings on the related topic | Öğretim Yöntemleri: Soru-Cevap |
| 2 | Biyomoleküllerin fiziksel, kimyasal, yapısal özellikleri, biyolojik fonksiyonları 2 (proteins) | Readings on the related topic | Öğretim Yöntemleri: Tartışma |
| 3 | Biyomoleküllerin fiziksel, kimyasal, yapısal özellikleri, biyolojik fonksiyonları 3 (proteins) | Readings on the related topic | Öğretim Yöntemleri: Soru-Cevap |
| 4 | Biyomoleküllerin fiziksel, kimyasal, yapısal özellikleri, biyolojik fonksiyonları 4 (lipids) | Readings on the related topic | Öğretim Yöntemleri: Soru-Cevap |
| 5 | Biyomoleküllerin fiziksel, kimyasal, yapısal özellikleri, biyolojik fonksiyonları 5 (lipids) | Readings on the related topic | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 6 | Biyomoleküllerin fiziksel, kimyasal, yapısal özellikleri, biyolojik fonksiyonları 6 (nucleic acids) | Readings on the related topic | Öğretim Yöntemleri: Tartışma, Bireysel Çalışma |
| 7 | Biyomoleküllerin fiziksel, kimyasal, yapısal özellikleri, biyolojik fonksiyonları 7 (nucleic acids) | Readings on the related topic | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | none | Ölçme Yöntemleri: Ödev, Performans Değerlendirmesi |
| 9 | Protein ayırma tekniklerinin temel prensipleri (Electrophoresis and Chromatography) | Readings on the related topic | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar |
| 10 | Protein ayırma tekniklerinin temel prensipleri (Jel Elektrofororezi Chromatography) | Readings on the related topic | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 11 | Protein ayırma tekniklerinin temel prensipleri (Kapiller Elektroforezi, Kütle Spektrometrisi) | Readings on the related topic | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 12 | Akım sitometri temel ilkeleri | Readings on the related topic | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar |
| 13 | Moleküler Yöntemlerin temelleri 1 | Readings on the related topic | Öğretim Yöntemleri: Soru-Cevap |
| 14 | Moleküler Yöntemlerin Temelleri 2 | Readings on the related topic | Öğretim Yöntemleri: Soru-Cevap, Bireysel Çalışma |
| 15 | Article criticim | Readings on the related topic | Öğretim Yöntemleri: Bireysel Çalışma |
| 16 | Term Exams | none | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav |
| 17 | Term Exams | none | Ölçme Yöntemleri: Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 12 | 5 | 60 |
| Out of Class Study (Preliminary Work, Practice) | 11 | 3 | 33 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 3 | 10 | 30 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 1 | 1 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 125 | ||
| Total Workload / 25 (h) | 5,00 | ||
| ECTS | 5 ECTS | ||