TÜRKÇE
ENGLISH
Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECF123 |
| Name | Mathematics - Biostatistics |
| Term | 2025-2026 Academic Year |
| Semester | 1. Semester |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Label | BS Basic Science Courses C Compulsory |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. İLKER ÜNAL |
| Course Instructor |
Prof. Dr. İLKER ÜNAL
(Güz)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
It is aimed that students gain knowledge of basic statistical notion in post graduation and pharmacy application fields and have knowledge about statistical concepts which are encountered in and after pharmacy education.
Course Content
The content of the ECF 115 Mathematics-Biostatistics course begins with fundamental definitions such as population, sample, and variable, and covers the classification of data types (nominal, ordinal, interval/ratio) and their presentation in appropriate tables or graphs, as well as appropriate analysis methods for each data type. Students learn to calculate confidence intervals used to estimate population values, along with measures of central tendency and dispersion used to summarize data, the assumption of normal distribution, and the concept of random error. Course topics include parametric methods such as independent and dependent samples t-tests, ANOVA, correlation, and regression, as well as non-parametric tests such as Mann-Whitney U and Wilcoxon, which are used when the assumptions of parametric methods are not met. Furthermore, various Chi-square tests used in the analysis of nominal data, risk measures such as Relative Risk and Odds Ratio, and the interpretation of statistical significance in light of clinical equivalence and "non-inferiority" concepts are taught. The final section of the course examines observational studies such as cross-sectional, case-control, and cohort studies, as well as experimental research designs including clinical trial phases, within the framework of the scientific evidence pyramid.
Course Precondition
None
Resources
Phillip Rowe «Essential Statistics for the Pharmaceutical Sciences» 2007 Chichester ; Hoboken, NJ : John Wiley and Sons
Notes
Prof. Dr. Reha Alpar. Spor, sağlık ve eğitim bilimlerinden örneklerle uygulamalı istatistik ve geçerlilik güvenirlik : SPSS'de çözümleme adımları ile birlikte, 4. Baskı, 2016
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Defines fundamental statistical concepts (population, sample, parameter, statistic, variable) and data scales (nominal, ordinal, interval, ratio). |
| LO02 | Calculates appropriate summarization criteria according to data type and characteristics, and presents them with tables and graphs. |
| LO03 | Explains the difference between statistical significance (p-value) and clinical significance (region of equivalence) through examples. |
| LO04 | Makes inferences about statistical analyses found in the pharmaceutical literature. |
| LO05 | Uses basic statistical knowledge to reason in the planning, execution, and conclusion phases of research. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 3 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 4 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 5 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 2 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | 2 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | 2 |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Data types and data presentation | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 2 | Interval scale data - Descriptive statistics | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 3 | Interval scale data - Normal distribution, Standard error and confidence interval | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 4 | Interval scale data - Hypothesis tests | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 5 | Interval scale test - Student's t test | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 6 | Interval scale test - Statistical significance, clinical significance | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 7 | Interval scale data - Paired t test | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 8 | Mid-Term Exam | Studying the appropriate chapter in the given resource book | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Interval scale data - ANOVA, Correlation and Regression | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 10 | Nominal scale data - Descriptive statistics, Goodness of fit Chi square test | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 11 | Nominal scale data - Chi square test | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 12 | Nominal scale data - Other Chi square tests, RR, OR and NNT | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 13 | Ordinal scale data - Transformation and nonparametric tests | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 14 | Nominal scale data - RR, OR and NNT | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 15 | Study designs - Observational and Experimental studies | Studying the appropriate chapter in the given resource book | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 16 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Midterm Exam | 100 | 40 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 1 | 4 | 4 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 10 | 10 |
| Total Workload (Hour) | 64 | ||
| Total Workload / 25 (h) | 2,56 | ||
| ECTS | 3 ECTS | ||