TÜRKÇE
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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| PEDIATRIC ONCOLOGY (MASTER) (WITH THESIS) | |
| Code | PEDO503 |
| Name | HLA Typing |
| Term | 2025-2026 Academic Year |
| Term | Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. GÜLAY SEZGİN |
| Course Instructor |
The current term course schedule has not been prepared yet.
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Course Goal / Objective
Understands the importance of HLA system in organ tranplants and disease pathogenesis
Course Content
HLA typing, its importance and applications
Course Precondition
-
Resources
https://www.nmdp.org/patients/understanding-transplant/finding-a-donor/hla-typing-matching
Notes
https://www.uptodate.com/contents/human-leukocyte-antigens-hla-a-roadmap
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Defines HLA system |
| LO02 | Understands HLA tissue types |
| LO03 | Gains competence in HLA typing methods |
| LO04 | Gains competence in use of HLA typing in organ transplants |
| LO05 | Gains competence in use of HLA typing in cellular therapies |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Belirsiz | They gain expertise in donor selection. | |
| PLO02 | Belirsiz | During the stem cell transplantation process, the most suitable graft is selected. | |
| PLO03 | Belirsiz | It lists the characteristics of donors according to the type of stem cell transplant. | |
| PLO04 | Belirsiz | It explains the concepts of haploidentical and allogeneic transplantation. | |
| PLO05 | Belirsiz | It lists the principles for collecting stem cells from cord blood. | |
| PLO06 | Belirsiz | This describes the steps involved in collecting CD34 cells from peripheral blood. | |
| PLO07 | Belirsiz | It describes the necessary conditions for collecting stem cells from bone marrow. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Definition of HLA and history | Öğretim Yöntemleri: Anlatım |
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| 2 | HLA tissue types | Öğretim Yöntemleri: Anlatım |
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| 3 | HLA tissue typing methods | Öğretim Yöntemleri: Anlatım |
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| 4 | HLA tissue typing laboratory | Öğretim Yöntemleri: Alıştırma ve Uygulama |
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| 5 | HLA tissue typing laboratory | Öğretim Yöntemleri: Alıştırma ve Uygulama |
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| 6 | HLA nomenclature | Öğretim Yöntemleri: Anlatım |
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| 7 | What does HLA match mean? | Öğretim Yöntemleri: Alıştırma ve Uygulama |
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| 8 | Mid-Term Exam | ||
| 9 | HLA typing in organ transplants | Öğretim Yöntemleri: Anlatım |
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| 10 | HLA and disease associations | Öğretim Yöntemleri: Anlatım |
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| 11 | HLA tissue typing laboratory | Öğretim Yöntemleri: Alıştırma ve Uygulama |
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| 12 | HLA tissue typing laboratory | Öğretim Yöntemleri: Alıştırma ve Uygulama |
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| 13 | Homework | Öğretim Yöntemleri: Bireysel Çalışma |
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| 14 | Homework | Öğretim Yöntemleri: Bireysel Çalışma |
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| 15 | Homework presentation | Öğretim Yöntemleri: Gösteri |
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| 16 | Term Exams | Öğretim Yöntemleri: Proje Temelli Öğrenme |
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| 17 | Term Exams | Ölçme Yöntemleri: Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 8 | 10 | 80 |
| Out of Class Study (Preliminary Work, Practice) | 2 | 2 | 4 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 6 | 6 | 36 |
| Mid-term Exams (Written, Oral, etc.) | 2 | 2 | 4 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 125 | ||
| Total Workload / 25 (h) | 5,00 | ||
| ECTS | 5 ECTS | ||