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| Unit | ABDİ SÜTCÜ HEALTH SERVICES VOCATIONAL SCHOOL |
| Code | TL243 |
| Name | Advanced Biochemistry |
| Term | 2026-2027 Academic Year |
| Semester | 3. Semester |
| Duration (T+A) | 3-4 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 5 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Label | C Compulsory |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. SEDEFGÜL YÜZBAŞIOĞLU ARIYÜREK |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
By the end of this course, students are expected to gain knowledge and skills regarding biochemical disorders that cause disease manifestations in medical biochemistry laboratories, as well as advanced analytical techniques commonly used in diagnosis and important in differential diagnosis.
Course Content
This course will cover topics related to the metabolisms of biomolecules, their disorders, disease manifestations, and analyses used in diagnosis and differential diagnosis.
Course Precondition
None
Resources
Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, Carl A. Burtis, Edward R. Ashwood, David E. Bruns, 2012
Notes
Lessons notes, Khan Academy Videos
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | It interprets the metabolisms of biomolecules that make up the basic structure of the human body and the connections between metabolic pathways. |
| LO02 | Diseases arising from metabolic disorders |
| LO03 | They will apply analyses used in the diagnosis related to disease manifestations. |
| LO04 | Defines basic concepts related to analytical techniques. |
| LO05 | Explains preanalytical variables. |
| LO06 | Lists qualitative and quantitative analysis methods. |
| LO07 | It performs analytical processes and quality control applications. |
| LO08 | It explains biochemical analysis techniques and their working principles. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explains the basis of human normal structure and function | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Defines disinfection, sterilization and hygiene. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Recognizes laboratory tools- materials, and measurement methods. | 2 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Explains the procedures to be performed in these phases using detailed information on the preanalytical, analytical and postanalytical phases of measurements. | 4 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Receives and accepts biological materials taken from the patient, prepares them for analysis and ensures that they are preserved under appropriate conditions if necessary. | 3 |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Performs internal and external quality control studies of the analyzes, analyzes patient samples after applying daily control procedures, checks the results and reports to the laboratory specialist. | 3 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Performs the calibration and maintenance of laboratory equipments, have them to be calibrated and maintained and monitored by authorized persons as needed, so that they work most efficiently | 4 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Determines inaduquaciesis in the laboratory | |
| PLO09 | Bilgi - Kuramsal, Olgusal | It provides coordination by reporting critical values to the clinician in the most appropriate and rapid way. | 4 |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | After graduation, he/she develops himself/herself and his/her career by following technological developments and critically evaluating the information he/she has learned with his/her own knowledge. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Having professional and ethical responsibility, they communicate well with colleagues, patients and physicians. | |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Uses at least one foreign language to follow developments in his field and to communicate with colleagues adequately. | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Takes measures regarding health, biosafety and occupational safety in the work environment. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Diseases related to protein metabolism and analyses performed in diagnosis | Reading from sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Carbohydrate metabolism-related diseases and diagnostic analyses | Reading from sources | Öğretim Yöntemleri: Anlatım, Tartışma, Deney / Laboratuvar |
| 3 | Lipid metabolism-related diseases and diagnostic analyses | Reading from sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösteri |
| 4 | Factors affecting enzyme activity, regulation, and the importance of enzymes in diagnosis | Reading from sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 5 | Structure, properties, synthesis of nucleic acids, and diagnostic analyses for anomalies | Reading from sources | Öğretim Yöntemleri: Anlatım, Tartışma, Gösteri |
| 6 | Diagnostic analyses in endocrine disorders | Reading from sources | Öğretim Yöntemleri: Anlatım, Tartışma, Deney / Laboratuvar |
| 7 | Properties, classifications, functions, and biological importance of vitamins | Reading from sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 8 | Mid-Term Exam | Preparing for exams using lecture notes and sources | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Collection and preparation of biological analysis materials for analysis | Reading from sources | Öğretim Yöntemleri: Anlatım, Tartışma, Deney / Laboratuvar |
| 10 | Basic concepts in analytical techniques | Reading from sources | Öğretim Yöntemleri: Anlatım, Tartışma |
| 11 | Qualitative techniques | Reading from sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösterip Yaptırma |
| 12 | Quantitative techniques | Reading from sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösterip Yaptırma |
| 13 | Calibration of biochemical analyzers | Reading from sources | Öğretim Yöntemleri: Soru-Cevap, Gösterip Yaptırma |
| 14 | Internal quality control applications in biochemical analyses | Reading from sources | Öğretim Yöntemleri: Anlatım, Tartışma, Bireysel Çalışma |
| 15 | External quality control applications in biochemical analyses | Reading from sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösteri |
| 16 | Term Exams | Preparing for exams using lecture notes and sources | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Preparing for exams using lecture notes and sources | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 7 | 98 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 5 | 5 |
| Final Exam | 1 | 10 | 10 |
| Total Workload (Hour) | 127 | ||
| Total Workload / 25 (h) | 5,08 | ||
| ECTS | 5 ECTS | ||