Information
| Unit | INSTITUTE OF NATURAL AND APPLIED SCIENCES |
| BIOTECHNOLOGY (MASTER) (WITH THESIS) (INTERDISCIPLINARY) | |
| Code | BT572 |
| Name | Biotechnology in Fish Disease Management |
| Term | 2026-2027 Academic Year |
| Term | Fall |
| Duration (T+A) | 4-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 4 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. SELÇUK DUMAN |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
To provide advanced knowledge on biotechnological methods used in the diagnosis, control and management of fish diseases and to enable students to evaluate modern molecular approaches in disease management.
Course Content
Biotechnological methods used in the diagnosis, monitoring and control of bacterial, viral, fungal and parasitic diseases in fish are discussed. Molecular diagnostic techniques, vaccine development, immunostimulants, biomarker analyses, omics technologies and sustainable disease management approaches are covered.
Course Precondition
No prerequisites
Resources
Woo, P. T. K., & Bruno, D. W. (2011). Fish Diseases and Disorders (Vol. 3: Viral, Bacterial and Fungal Infections). CABI.
Notes
Austin, B., & Austin, D. A. (2016). Bacterial Fish Pathogens: Disease of Farmed and Wild Fish. Springer. Woo, P. T. K., & Bruno, D. W. (2011). Fish Diseases and Disorders (Vol. 3: Viral, Bacterial and Fungal Infections). CABI. Roberts, R. J. (2012). Fish Pathology (4th ed.). Wiley-Blackwell. Ellis, A. E. (2012). Fish Vaccination. Wiley-Blackwell. Duman, S. (2020). Effect of concrete pond and net-cage culture systems on growth performance andhaematological parameters of Siberian sturgeon (Acipenser baerii). Turkish Journal of Veterinary & Animal Sciences, 44(3), 624-631. Duman, S., & Şahan, A. (2018). Some hematological and non-specific immune responses of rosehip (Rosa canina)-Fed Russian Sturgeon (Acipenser gueldenstaedtii Brandt & Ratzeburg, 1833) to Mycobacterium salmoniphilum. Brazilian Archives of Biology and Technology, 61, e18180283. Duman, S. (2019). The effect of anesthetic (2-phenoxyethanol) application on some biochemical and hematological parameters in Russian sturgeon (Acipenser gueldenstaedtii) and Siberian sturgeon (Acipenser baerii) during transport. Turkish Journal of Veterinary & Animal Sciences, 43(6), 825-833. Duman, S. (2020). Determination of reference values of some hematological and immunological parameters in healthy Russian sturgeon (Acipenser gueldenstaedtii). Journal of Anatolian Environmental and Animal Sciences, 5(2), 212-217. Duman, S., & Şahan, A. (2023). Effects of β-1, 3/1, 6 glucan dietary supplements on some immunological and hematological health markersin Siberian sturgeon (Acipenser baerii) infected with Aeromonas hydrophila. Polish Journal of Veterinary Sciences, 109-118. Current articles indexed in SCI and SCI-Expanded related to the field will be followed within the scope of the course.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explains the molecular and cellular mechanisms of fish diseases |
| LO02 | Evaluates molecular diagnostic techniques (PCR, qPCR, etc.) |
| LO03 | Explains fish vaccines and vaccine development processes |
| LO04 | Analyzes immunostimulants and biological control methods |
| LO05 | Interprets the use of biomarkers and omics technologies |
| LO06 | Evaluates antimicrobial resistance and alternative solution strategies |
| LO07 | Plans sustainable disease management approaches |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on undergraduate level qualifications, they develop their knowledge at the level of expertise in the same or a different field. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Knows the ethical rules to be considered while obtaining biotechnological products. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | To identifiy the interdisciplinary interaction of the field and to solve use of the methods. | |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Interpret the knowledge gained in the field by integrating the information from different disciplines and creates new information | 3 |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Develops new strategic approaches for solving complex problems that are encountered in applications related to the field. | 3 |
| PLO06 | Yetkinlikler - Öğrenme Yetkinliği | To teach the social, scientific, cultural and ethical values during the collection, interpretation, implementation and announcement of the data related to the field. | |
| PLO07 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | To solve the problems encountered in the field and cominicate by using research methods. | |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Establishes functional interaction by using strategic decision-making processes in solving the problems encountered in the field. | |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. | |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | To gain the ability to develop and deepen the knowledge in the field of biotechnology | 5 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Disease management and biotechnology in aquaculture. | Review of primary sources and the proposed article. | Öğretim Yöntemleri: Soru-Cevap |
| 2 | Fish immune system and molecular mechanisms. | Review of primary sources and the proposed article. | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 3 | Bacterial diseases and molecular pathogenesis | Review of primary sources and the proposed article. | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 4 | Viral diseases and genome structures. | Review of primary sources and the proposed article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 5 | Parasitic and fungal diseases | Review of primary sources and the suggested article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 6 | Molecular diagnostic methods (PCR, qPCR) | Review of primary sources and the proposed article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 7 | Rapid diagnostic systems and biosensors | Review of primary sources and the proposed article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 8 | Mid-Term Exam | Review of lecture notes, weekly resources, and previous topics | Ölçme Yöntemleri: Sözlü Sınav |
| 9 | Fish vaccines and biotechnological production | Examination of primary sources and the suggested article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 10 | Immunostimulants and probiotics | Examination of primary resources and the suggested article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 11 | Antimicrobial resistance and alternative solutions | Examination of primary sources and the suggested article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 12 | Genetic selection and disease resistance | Examination of primary sources and the suggested article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 13 | Omics technologies (transcriptomics, proteomics) | Examination of primary resources and the proposed article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 14 | Sustainable disease management | Examination of key resources and the suggested article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 15 | Evaluating current research | Examining primary sources and the suggested article | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 16 | Term Exams | Reviewing lecture notes, weekly resources, and previous topics | Ölçme Yöntemleri: Sözlü Sınav |
| 17 | Term Exams | Reviewing lecture notes, weekly resources, and previous topics | Ölçme Yöntemleri: Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 10 | 2 | 20 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 2 | 2 |
| Final Exam | 1 | 2 | 2 |
| Total Workload (Hour) | 150 | ||
| Total Workload / 25 (h) | 6,00 | ||
| ECTS | 6 ECTS | ||