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Information
| Unit | INSTITUTE OF NATURAL AND APPLIED SCIENCES |
| BIOTECHNOLOGY (MASTER) (WITH THESIS) (INTERDISCIPLINARY) | |
| Code | BT575 |
| Name | Neurobiophysics |
| Term | 2026-2027 Academic Year |
| Term | Fall |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. ÇAĞIL COŞKUN |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
Neurobiophysics is an interdisciplinary field that examines the nervous system, the developmental processes of neurons, and the effects of neural networks on function from a biophysical perspective. The aim of this course is to understand the formation and differentiation of neurons, neural activity, signal transmission, and underlying molecular mechanisms; to examine the contributions of different brain regions to cognitive and behavioral functions; and, in this context, to learn about related damage, its physiological consequences, as well as mechanisms of injury and repair. The objective of the course is to provide students with a foundation for the development of appropriate biotechnological products related to the nervous system and brain injuries by teaching the mechanisms of the nervous system, cognitive-behavioral processes, and associated pathological damage.
Course Content
Neurons, their differentiation, and neural circuit formation; Fundamentals of neuronal information transmission I – biopotentials; Fundamentals of neuronal information transmission II – synaptic transmission and neurotransmitters; The brain and its functional regions; Modulation of neurons and synaptic connections; Mechanisms of nervous system injury and repair; Pain and mechanisms of pain; Neurophysiology of epilepsy; Neurophysiology of sleep; Neurophysiology of schizophrenia; Learning and memory: neurophysiology of Alzheimer’s disease; Neurophysiology of autism and anxiety; Role of technology in the treatment of nervous system injuries – current approaches.
Course Precondition
none
Resources
Principles of Neural Science, Sixth Edition (Eric Kandel)
Notes
Principles of Neural Science, Sixth Edition (Eric Kandel)
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Gains knowledge about the formation and differentiation of nervous system cells. |
| LO02 | Gains knowledge about neuronal signal transmission. |
| LO03 | Learns the neuronal and molecular mechanisms underlying cognitive and behavioral processes. |
| LO04 | Learns the mechanisms of nervous system injury and repair. |
| LO05 | Gains knowledge about the cellular and molecular mechanisms of major neuronal dysfunction disorders and neurodegenerative diseases. |
| LO06 | Gains knowledge about current and emerging technologies targeting the nervous system. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on undergraduate level qualifications, they develop their knowledge at the level of expertise in the same or a different field. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Knows the ethical rules to be considered while obtaining biotechnological products. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | To identifiy the interdisciplinary interaction of the field and to solve use of the methods. | 4 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Interpret the knowledge gained in the field by integrating the information from different disciplines and creates new information | 4 |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Develops new strategic approaches for solving complex problems that are encountered in applications related to the field. | 4 |
| PLO06 | Yetkinlikler - Öğrenme Yetkinliği | To teach the social, scientific, cultural and ethical values during the collection, interpretation, implementation and announcement of the data related to the field. | |
| PLO07 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | To solve the problems encountered in the field and cominicate by using research methods. | |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Establishes functional interaction by using strategic decision-making processes in solving the problems encountered in the field. | |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. | |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | To gain the ability to develop and deepen the knowledge in the field of biotechnology | 5 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Neurons, their differentiation, and the establishment of neural circuits | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Fundamentals of Neuronal Information Transmission I – Biopotentials | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Fundamentals of Neuronal Information Transmission II – Synaptic Transmission and Neurotransmitters | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | The Brain and Its Functional Regions | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Modulation of Neurons and Synaptic Connections | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Mechanisms of Nervous System Injury and Repair | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Pain and Its Mechanisms | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav |
|
| 9 | Neurobiophysics of Epilepsy | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Neurobiophysics of Sleep | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Neurobiophysics of Schizophrenia | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Learning and Memory: Neurobiophysics of Alzheimer’s Disease | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Neurobiophysics of Autism and Anxiety Disorders | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | The Role of Technology in the Treatment of Nervous System Injuries – Current Approaches I | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | The Role of Technology in the Treatment of Nervous System Injuries – Current Approaches II | Reading the relevant section from the sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 15 | 15 |
| Total Workload (Hour) | 114 | ||
| Total Workload / 25 (h) | 4,56 | ||
| ECTS | 5 ECTS | ||