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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| BIOSTATISTICS (MEDICINE) (MASTER) (WITH THESIS) | |
| Code | BİS505 |
| Name | Survival Analysis in Health Research |
| Term | 2026-2027 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 1-3 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2.5 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi Sevinç Püren YÜCEL KARAKAYA |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
The objective of this course is to teach the basic methods used for analyzing survival data in health research and to enable students to gain the skills to analyze data using appropriate statistical techniques, interpret results, and report findings.
Course Content
This course covers the basic concepts of survival analysis, censored data, the Kaplan-Meier method, comparison of survival curves, the Cox regression model, and areas of application in health research.
Course Precondition
No
Resources
Hosmer Jr, D. W., Lemeshow, S., & May, S. (2008). Applied survival analysis: regression modeling of time-to-event data. John Wiley & Sons. Lee, E. T., & Wang, J. (2003). Statistical methods for survival data analysis (Vol. 476). John Wiley & Sons.
Notes
Hosmer Jr, D. W., Lemeshow, S., & May, S. (2008). Applied survival analysis: regression modeling of time-to-event data. John Wiley & Sons. Lee, E. T., & Wang, J. (2003). Statistical methods for survival data analysis (Vol. 476). John Wiley & Sons.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explain the basic concepts of survival analysis. |
| LO02 | Define the structure of survival data and types of censoring. |
| LO03 | Estimate and interpret survival probabilities using the Kaplan-Meier method. |
| LO04 | Evaluate differences between groups using appropriate survival comparison tests. |
| LO05 | Explain the basic principles of the Cox regression model and interpret its results. |
| LO06 | Report survival analysis results in health research. |
| LO07 | Perform basic survival analysis using statistical software packages |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Students comprehends the fundamentals of statistical theory related to the field of health ( probability and bayesian biostatistics). | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Students explain demographic terminologies and statistical methods in the field of health sciences. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Students understand and use medical terminology. | 2 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Students collect data from research studies, analyze, and make inferences | 2 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Students knows the system of international classification of diseases, obtain and analyze hospital statistics. | |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Students design scientific research studies in order to give response to the problem arising from health and clinical sciences | 2 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Students select the appropriate statistical procedure for analysis , apply and make inferences. | 3 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Students use the necessary statistical packages for analysis, if necessary write and develop software. | 2 |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Students follow the latest development in medical informatics and employ frequently used tools and methods. | |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Students design health survey, determine the sampling method and conduct the survey | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Students select and use proper statistical procedure for diagnosis and in making inferences for the data in health and clinical medicine and provide consultance to clinicians in the field. | |
| PLO12 | Yetkinlikler - Öğrenme Yetkinliği | Students develop the ability of critical thinking, make a conclusion with a critical approach to the evidence | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Students apply analytical procedure to frequently used survival data, multivariate procedure and regression techniques. | 5 |
| PLO14 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Students provide consulting services by using effective communication skills; take part in research teamworks; defend the ethical rules. | |
| PLO15 | Yetkinlikler - Alana Özgü Yetkinlik | Students explain the fundamental terminologies in epidemiology, guide researchers conducting field survey and clinical studies, develop methodologies in determining disease risk factor and disease burden and advise for choosing proper diagnostic test. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to Survival Analysis and Basic Concepts | Reading | Öğretim Yöntemleri: Anlatım |
| 2 | Structure of Survival Data and Censoring | Reading | Öğretim Yöntemleri: Anlatım |
| 3 | Survival and Hazard Functions | Reading | Öğretim Yöntemleri: Anlatım |
| 4 | Life Table Method | Reading | Öğretim Yöntemleri: Anlatım |
| 5 | Kaplan-Meier Method | Reading | Öğretim Yöntemleri: Anlatım |
| 6 | Group Comparisons in Survival Analysis I | Reading | Öğretim Yöntemleri: Anlatım |
| 7 | Group Comparisons in Survival Analysis II | Reading | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav |
|
| 9 | Applications in Survival Analysis | Reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 10 | Cox Regression I | Reading | Öğretim Yöntemleri: Anlatım |
| 11 | Cox Regression II | Reading | Öğretim Yöntemleri: Anlatım |
| 12 | Computer Applications in Survival Analysis I | Reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 13 | Computer Applications in Survival Analysis II | Reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 14 | Examples of Survival Analysis in Health Research | Reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 15 | Reporting Survival Analysis Results | Reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 4 | 4 |
| Final Exam | 1 | 4 | 4 |
| Total Workload (Hour) | 106 | ||
| Total Workload / 25 (h) | 4,24 | ||
| ECTS | 4 ECTS | ||