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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| MEDICAL BIOLOGY (PhD) | |
| Code | BİO001 |
| Name | Current Molecular Biology and Genetics Topics 1 |
| Term | 2024-2025 Academic Year |
| Term | Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 15 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. AYFER PAZARBAŞI |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
To provide students with information about the topics that are currently discussed and researched in the field of molecular biology and genetics and to gain perspectives that can make scientific studies on these topics.
Course Content
Articles on topics that are currently discussed and researched in the specified field.
Course Precondition
No Prerequisites.
Resources
Articles in the literature on the identified topics.
Notes
Articles in the literature on the identified topics.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | To have an idea about where to start when he wants to do scientific work on the subject covered in the course. |
| LO02 | To understand the importance of multidisciplinary studies and to have knowledge about multidisciplinary studies. |
| LO03 | To have knowledge about molecular techniques and bioinformatics methods currently used in scientific research. |
| LO04 | To have knowledge about the various effects that different signalling pathways and mechanisms active in the cell can have on the genome. |
| LO05 | To have knowledge about current gene therapy approaches. |
| LO06 | To have knowledge about cancer biology, cancer immunotherapy and tools used in cancer treatment. |
| LO07 | To have knowledge about genetic mechanisms and epigenetic changes that play a role in the aging process. |
| LO08 | To have knowledge about stem cell biology, regenerative medicine and personalised therapy. |
| LO09 | To have knowledge about the effects of microbiome. |
| LO10 | To have knowledge about the conditions in which the immune system is affected and affected. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To make and interpret Medical Genetics, Molecular Genetics and Cytogenetic analyzes | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | To have information about genetic diseases | 4 |
| PLO03 | Bilgi - Kuramsal, Olgusal | To have knowledge of Molecular Cell Biology | 5 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | To apply fluorescence in-situ hybridization (FISH) technique | |
| PLO05 | Yetkinlikler - Alana Özgü Yetkinlik | To make DNA isolation and PCR of all kinds of tissue | |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | To make cell culture of all kinds of tissue (blood, amniotic fluid, chorionic villus biopsy) | |
| PLO07 | Bilgi - Kuramsal, Olgusal | To do cytogenetic analysis by recognizing human chromosomes separately | |
| PLO08 | Bilgi - Kuramsal, Olgusal | To make QF-PCR and to interpret the results | |
| PLO09 | Bilgi - Kuramsal, Olgusal | To have the knowledge and skills to teach Medical Biology and Genetics Courses in Medical Faculties | 4 |
| PLO10 | Bilgi - Kuramsal, Olgusal | To write and implement a research project on his/her own | 3 |
| PLO11 | Yetkinlikler - Öğrenme Yetkinliği | To write an article by collecting the information obtained at the end of the research | 4 |
| PLO12 | Yetkinlikler - Öğrenme Yetkinliği | To organize laboratory courses of Medical Biology and Genetics courses at undergraduate level |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Molecular techniques currently used in scientific research. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 2 | Bioinformatics tools that can be used for scientific research. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 3 | The effect of signalling pathways active in the cell on the genome. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 4 | Molecular basis of common genetic diseases. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 5 | Stem cell biology and regenerative medicine. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 6 | Genetics of cancer and cancer stem cells. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 7 | Effects of epigenetic regulation. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 8 | Effects of the human microbiome. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 9 | Conditions in which immune system mechanisms are affected and affected. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 10 | Genetics of ageing. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 11 | Synthetic biology. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 12 | Next generation immunotherapies in cancer. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 13 | RNA-based therapies. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 14 | Personalised treatment. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 15 | Principles of gene therapy and current gene therapy approaches. | Literature review and article reading on the determined topic. | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 16 | Term Exams | Ölçme Yöntemleri: Sözlü Sınav |
|
| 17 | Term Exams | Ölçme Yöntemleri: Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 15 | 3 | 45 |
| Out of Class Study (Preliminary Work, Practice) | 15 | 8 | 120 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 15 | 14 | 210 |
| Mid-term Exams (Written, Oral, etc.) | 0 | 0 | 0 |
| Final Exam | 1 | 2 | 2 |
| Total Workload (Hour) | 377 | ||
| Total Workload / 25 (h) | 15,08 | ||
| ECTS | 15 ECTS | ||