TÜRKÇE
ENGLISH
Information
| Code | BL448 |
| Name | Antibiotics and Their Influence Mechanisms |
| Term | 2024-2025 Academic Year |
| Semester | 8. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. HATİCE GÜVENMEZ |
| Course Instructor |
1 2 |
Course Goal / Objective
The aim of this course is to teach the targets and effects of chemical and biological antimicrobial agents on microorganisms, the behavior of microorganisms against these agents and the resistance mechanisms they develop.
Course Content
Bu derste kimyasal antimikrobiyal ajanlar, mikrobiyal büyümenin kontrolü ve bir antimikrobiyal ajanın in vivo kullanıldığında organizmada izlediği yol, antimikrobiyal ajanların uygulama yerleri ve yolları, Antibiyotiklerin hedefleri Sentetik antimikrobiyal ilaçlar Doğal antimikrobiyal ilaçlar: Antibiyotikler Hücreyi inhibe eden antibiyotikler duvar biyosentezi: Penisilinler, sefalosporinler, basitrasin, karbapenem, monobaktam, vankomisin Protein sentezini inhibe eden antibiyotikler: makrolidler, aminoglikozidler, tetrasiklinler, linkozamidler DNA giraz inhibitörleri; Kinolonlar (Nalidiksik asit) Lipid biyosentezini durduranlar, Folik asit metabolizmasında etkili olan antimikrobiyal ajanlar, Sitoplazmik membran yapısını ve fonksiyonunu etkileyen antimikrobiyal ajanlar; Polimiksinler, Daptomisin Antiviral ajanlar Antifungal ajanlar ve Antiparaziter ajanlar kapsanmaktadır
Course Precondition
None
Resources
Antibiotics Prof. Dr. Hakan LEBLEBİCİOĞLU - Prof. Dr. Gaye USLUER - Prof. Dr. Sercan ULUSOYBrock, Biology of Microorganisms, 14th Edition
Notes
Brock, Biology of Microorganisims 14ed.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | explains the effects of antimicrobial agents and resistance mechanisms of microorganisms |
| LO02 | explains the antimicrobial agent pathways in the use of anorganism in vivo |
| LO03 | Explains the application sites and pathways of antimicrobial agents |
| LO04 | Lists the targets of antibiotics |
| LO05 | Classifies synthetic antimicrobial drugs. |
| LO06 | Indicates antimicrobial agents effective in folic acid metabolism. |
| LO07 | Explain the antiviral agents |
| LO08 | Lists the Protein synthesis inhibitors |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explain the basic concepts and principles in biology | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | The knowledge gained in the field of biology combine with information from other sciences. | 3 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Identifies problems in the field of biology and apply methods for their solution | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Describes the method of producing scientific knowledge in the field of biology | 3 |
| PLO05 | Bilgi - Kuramsal, Olgusal | They will receive information on the biology area, in order to classify it uses and purposes. | 3 |
| PLO06 | Bilgi - Kuramsal, Olgusal | They use advanced theoretical and practical knowledge that obtain in biology field. | |
| PLO07 | Bilgi - Kuramsal, Olgusal | They are Field-related issues can inform the relevant persons and institutions, They share ideas and problems relating to suggestions as the written, oral and Visual to expert or transfer to non-experts. | 2 |
| PLO08 | Bilgi - Kuramsal, Olgusal | They can take responsibility as individuals and team members to solve unpredictable problems encountered in applications related to the field. | 3 |
| PLO09 | Bilgi - Kuramsal, Olgusal | they can take an active role as a member of the execution team the planning of projects related to the field. | 3 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | They know that life-long learning process and act accordingly. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They will increase the knowledge and experience outside major issues with specific elective courses in different fields of biology. | |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They speak English enough to communicate with colleagues to understand the basic concepts of biology. | |
| PLO13 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They both with colleagues, as well as areas with non-person establishes ethical uses of information and communication technology. In addition to professional development, in line with the interests and abilities of scientific, social, constantly improves itself by identifying learning needs in cultural and artistic fields. | |
| PLO14 | Yetkinlikler - Öğrenme Yetkinliği | They assesses developments in biology versatile using scientific methods and techniques | |
| PLO15 | Yetkinlikler - Öğrenme Yetkinliği | They know the importance of personal development and enforces the need. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Chemical antimicrobial agents, the control of microbial growth. | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 2 | The pathway of using in vivo in organism of an antimicrobial agent | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 3 | Places and ways of application of antimicrobial agents. | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma, Soru-Cevap |
| 4 | Targets of antibiotics | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 5 | Synthetic antimicrobial drugs | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma, Gösteri |
| 6 | Natural antimicrobial drugs: Antibiotics | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 7 | Cell wal synthesis inhibitors: Penicilline, cephalosporins, bacitracins, carbapenems, monobactam, vancomycine | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma, Beyin Fırtınası |
| 8 | Mid-Term Exam | An overview | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Protein synthesis inhibitors: macrolida, aminoglycoside, tetracycline, lincozamids | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 10 | DNA-gyrase inhibitors: Quinolons | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 11 | Lipid biosynthesis inhibitors | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 12 | Folic acid metabolism effective antimicrobial agents | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 13 | Antiviral agents | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma, Beyin Fırtınası |
| 14 | Antifungal agents | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 15 | Antiparasiter agents | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | An overview | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | An overview | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 4 | 4 | 16 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 12 | 12 |
| Total Workload (Hour) | 92 | ||
| Total Workload / 25 (h) | 3,68 | ||
| ECTS | 4 ECTS | ||